09-21-1954 12:12
5162825311
3NL-MED, DEPT.
P.005
-+-
purpa, and kypoxia due to anemia, any cone of which may be fatal.
Many
descriptions of the pathogenesis of these phenomena have been publishdd
The above picture
detailed (1-4,12-16).
of radiation syndromes is based on animal expdrimentation;
however, human experiences particularly as observed at Hiroshima and Nagasaki and
in the Marshallese natives has indicated that man probably correspoms
quite
closely to thea general mammalian response outlined sbowe with the exckption of
some differences in time of occurrencsa,
The CNS apparently was not observed by
the Japanese at Hiroshima and Nagasaki.
Cne would not expect it to hhve been
observai since Joses to produce this symirome vere well within the arpa of alnost
total destruction.
The GIS with deaths in the first week are well dobumented
clinically and patholovically os are deaths from the HS.
Nowever infthe case of man,
denths fron infection were most prevalent in the second to fourth vedks (maxdmum
ineldence durins the third week) ami from hemorrhasic vhenomena in tYe third to the
sixth weeks (maximum incidence in the fourth veek).
In the Japanese]
after the
bombing of Hiroshima and Nagesaki, deaths from radiation injuries wege occurring as
late as the seventh week.
This is in contrast to other animals wher$ deaths from
the acute phase are uncommon after the 30th day.
PRORASILITY OF SURVIVAL AS RELATED TO SYMPTOMS
Predictions of the effects of various doses of gamma radiation
to military and civil defense flanning.
If the absolute sensitivity,
bre essential
of man to
rediation were known, and if it were practical to determine the dos@to groups
under catastrophe comditions, a roalisti¢c statistical prognosis co
be made.
However, these predictions cannot be made accurately at the present
fiime.
involved with estimation of dose received by the individual, present]
real practical
difficulties.
[fron dosimetry
It is probable that dose estimates will be available
devices or from dose contour lines and the position of individuals
Problens
ing exposure.
The difficulties of relying heavily on the dose estimates for a single individual
are apparent,
The exact position of the individual and the degree
shielding