Volume 66, No. 6
June 1967
LATE EFFECTS OF RADIOACTIVE IODINE IN FALLOUT
1227
consistency, movable, and nontender. We
did not detect general glandular enlargement in most cases. Figure 10 shows one
of these glands at surgery, indicating the
nature of the nodules. Although someclini-
cians have doubted that we could palpate
2- to 3-mm nodules, our clinical estimate of
these tiny nodules was substantiated at sur-
gery. All subjects except adults (one with
cancer) were found to have adenomatous
goiter. Figure 1] shows a typical microscopic picture of a nodule with the bizarre
characteristics of varioussize follicles, some
of which were cystic and filled with colloid,
others hemorrhagic, others microfollicular,
12. Sections of these nodules have been
studied by a number of pathologists, and
a resemblance to the pattern of iodine deficiency goiter has been remarked upon.
Most claim that they cannotsee actual radi-
Ficure 10. Surgical exposure of thyroid showing
nodules (Case 17).
ation effects histologically. Figure 13 shows
the mixed follicular and papillary carci-
noma of the thyroid with blood vessel in-
vasion found in a 4l-year-old exposed
Ficure 11. Microscopic section of benign adenomatous nodule showing bizarre nature of follicles, some cystic, some microfollicular, some macrofollicular, and some hyperplastic. (Hema-
toxylin-eosin, x 16.)
Peteineanettiqe
others macrofollicular, and some with hyperplasia with infolding of the epithelium.
This hyperplasia is demonstrated in Figure