67
Hematological Effects on Heavily Irradiated Japanese Fishermen
se to each person differed dehis cabin.
‘YT was inferred as about 20 to
HEMATOLOGICAL OBSERVATIONS
ity in the thyroid region during
1.
> found in the urine samples
1. The radioactivity decrease
d
counts at about the 4th to 8th week after the exposure. Five cases revealed a
count of less than 2,000/mm2, 13 less than 3,000, and 5 less than 4,000. In
on the activity in the urine
was
rom the fatal case showed that
‘her, when compared with the
AIMURA et al., 1956).
“r content in the urine of
the
the same time the results cf
erence between fishermen and
Leukocytes
The total number of leukocytes decreased gradually, showing minimum
one case, the leukocyte level was depressed to 800.
Similar relationship was found between minimum counts ef neutrophils and
the dose as shown in Figure 2.
2500
w 2000
z&
lay an impotant role in early
sns in the early stage.
Fig. 2.
Correlation
between
the estimated doses to the whole
body and the minimal number
of neutrophils.
_
1500
oo
;
= 1900
ote
=
- EARLY STAGE
A correlation was found
between these minimum counts and the doses of inclividual external irradiation.
e
*e
500
—
_
yo
.”
.
bd
2
e
dose of lst day
70
dose during 2weeks 160
130
200
190
300
250
400
310
500
.
370
600
430
700
In most cases a shift to the left of the neutrophils was observed.
cells increased in early stage and then gradually decreased.
490
800
R
R
Staff
However, in
some cases, metamyelocytes and myelocytes appeared in peripheral blood
especially with the begin of recovery. In a fatal case who died of liver
damage, a considerable number of juvenile neutrophils were observed at the
end stage. Lymphopenia was noted between the 2nd and 8th week in all
cases. Leukocyte count began to increase after the 8th week. In manycases
eosinophilia was remarkable, especially with the indication cf recovery.
Eosinophilia continued in some cases for several years without proof of parasites,
and one case still revealed slight eosinophilia in the 1968 survey.
2.
Erythrocytes
At the time of hospitalization a few patients were anemic. Noreticulocyte
was observed in them at the critical stage. Color index was higher than1. 0.
The Price-Jones curves of erythrocyte diameter were displaced to the right
of normal atfirst, and returned to almost normalafter one year. These changes
corrseponded to changes of erythroblast diameters in bone marrow.
3.
Platelets, ete.
Platelet counts decreased, reaching a minimum in the 4th to 7th week.
Most of the fishermen revealed the values below 100,000/mm3.
Fig. 1 Symptons and signs
in
the early stage.
The results
of other tests related to hemorrhage showed depression at the critical stage
in general and recovered by the 10th week.
4.
Comparison with Other Irradiated Cases
When these blood changes are compared with the changes of other irradiated