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velopment of a case of leukosnia tend to support
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tnulative perceatage of neutrophils, lymphocytes,
and platelets at various tines. From these data it
Sppcars that hemepoichc recovery inthe exposed
Wroups was incomplete during the first 13 years
alice exposure, Since dhat time the levels in the expesed group have been about the same asin the
unexposed group. On the basis of KIC, hematyert, and hewoglobin determinations, ery Uiropoielie function has been about the same in the exposed and in the comparison population. Phe lag
in recovery Of leukocytes and platelets may reprewt residual bone auugrraw jajury. The results of
3. Bone Marrow
Atthough bone tiurrow cxaminsiions at 6
Thagths post expesure showed ne pros abnormal
ilies, sncans on lourespascd Runyclap people 10
years kuter showed alteration ian the myeloid.
crvthroid catio in three of thea, manifested by an
inereascd nanber uf eed och preeursors. da additen te hyperplasia. die tidings included abnor.
makities of Chromatin material with doubbe auch
atab an increased nunber af niitetic figures in the
ornabbastic series (sce Fiiures $4 and 1), 5) Oe.
casionally, bilaubed Iyvmphocyies have been noted
inthe peripheral bigod af some exposed people.
4. Other Hematological Findings
“Total blood volume and red cell volume were
studied 10 yours after exposure!!!" No differences
were found beaween exposed and wnexpesed Rone
selap groups, bat it was nated that blood valume
and red ecll velume tended tube reduced in many
Marshallese compared with Americans] (see Fig.
ure 16)! Severabarher hematological observa:
ions, net related to radbation exposure. were noted,
Losinopbilia >5% in anare than half the people
has been a consistent finding. This could be ac.
counted for anly partly an the basis of intestinal
parasivisin and may be related abso to mamerous
fungus intections af the skin aiid other chronic ine
fections, Other findings possibly rehired to chronic
Infections are above-normal sedimentation rates
wd bigh gamma globulin levels (both tending to
increas? with ave). Varving degrees of anemia
have been seen occasionally, particularly in wo-
*Phese studies were dhine ba De 1M. Mever, Veterans Ab
Hnistration Mapital. Aeaklyn, NOV. and be. WOE. Sin. Una.
senity of Caliernia at Hea beley,
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Figure 16.
men of childbearing age, Price Jones sizing of red
cells in these cases showed a slight microcytic tend.
ency.* Tron delicicney apparently was not the cause
since serum iron usually was in the pormal range.®
Keticulocyte counts have not been significantiv
icreased in either the exposed or unesaposed population. Miacroeytic ancinia bas nut been seen,
Vitansin Bye levels have been unusually high in
the Marshallese*; the cause of this is unknown but
does not appear tu be related tu liver disease or
keukemia. The sickling trait has not been seenin
the Marshallese examined.
D. SUBSEQUENT COURSE OF SKIN LESIONS
The residual skin lesions noted in the Rongclap
and Ailingnae people since the initial lesions are
listed in Table 15. During the first vear many of
the healed arcas, particularly on the back of the
neck, showed a roughening (rugosity) and bluish.
black pigmentation, which became less noticeable
with time (see Figures 17 and '8). Deeper lesions
exhibited carly residual scarring and lack of pig-