ea
Aodienits
a
a a ee
A
mle elietefli Me Ra An oth
™
stone:
Table 20
Growth and Thyroid Studies in Subjects With Thyroid Abnormalities
Neck 1327
Growth
abnormality
Year
tested
age, yr
Skeletal
ranking,
yr
Statural
—ranking,°
percentile
3 M_
Atrophy
1965
13
3
<10
5 M_
Atrophy
1965
13
5%.
<10
1966
1966
Pre
Post
TSH
TSH
Serum iodine,
ug
PBI
1.4
08
1.9
0.8
3.2
8
3.1
17
F
Nodular
goiter
1965
1966
15
13%2
90
6.8(°64)
1.8
21
F
Nodular
1965
15
15
10-25
8.1 (764)
69
F
Nodular
goiter
19654
1966!
16
16
2
M_
Nodular
1965
13
112
25-50
20
M_
Nodular
1965
19
Adult
25-50
72
F
Nodular
goiter
1965
18
17H2
>90
42
F
Nodular
goiter
1965
1966
15
13%2
10
61
F
Nodular
1965
20
Adult
50-75
54
M_
Noedular
1965
13
13
90
19
M_
Nodular
1965
17
15K2
10
36
M_
Nodular
1965
19
18
75
4.1
33.
*F
Nodular
1965
13
13%2
>90
7.0
65
F
Nodular
1965
13
10%2
<10
59
F
Solitary
nodule
1965
1966
35
64
F
Carcinoma
1965
31
40
M
Solitary
nodule
1965
40
goiter
goiter
goiter
goiter
goiter
goiter
goiter
goiter
goiter
1966?
1966¢
1966
1966
19664
1966
1966
1966
19664
.
>90
6.5
18
(29)
(23)
(31)
(31)
T,1
1.0
Serum
TSH,
ng/ml
>120
159
119
1.8
248
<0.5
372
1.3
<0.5
440
7.1
5.7
1.7
125
7.9
4.2
65
4.2
5.2
2.6
9.6
26.6
23
(15)
(24)
57
4.6
12°(10)
(24)
7.9
4.9
8.3
19
(24)
(9)
(14)
7°(20)
(38)
(19)
(28)
17
‘
<3
9.0
4.3
<b?
3.9
3.3
<17
4.3
<17
3.9
3.8
197
4.9
2.1
8.2
8.6
5.3
4.8
4.2
(16)
<17
3.1
8.6
4.9
19
7.3
6.6
23.5
3.4
2.0
10.3
«Values in parentheses obtained at BNL.
*Relative statural growth expressed as percentile ranking compared with growth curves of unexposed Marshallese
children.
“Assays in 1963 could not detect levels below 3 nanograms/ml. Seven unexposed children in the same age group had
<3 ngyml. Assays in 1966 could not detect levels below 17 ng/ml. Three exposed children without thyroid disease
(Nos. 6, 8, and 32) had <17 ng/ml. Two children exposed tn utero (Nos. 84 and 86) and two unexposed children had
<17 ng/ml. The 1966 levels were obtained about 3 weeks after cessation of thyroxine therapy, the 1965 levels. before
therapywas instituted. We are grateful to Dr. William Odell at the Nationa! Institutes of Health for carrying out these
assays.
‘Post partial thyroidectomy.
“While taking thyroxine.
ae
SHH g@29
fh
SOC
Sey
aemee, eee
and sex
Thyroid
Chronological
Mince
Subject
No.
at 4 hr,*
% of dose