Hematological E
T. KUMATORI
68
subjects, i.e. Hiroshima cases,
cidents (Hempetman et al., 1952 ;
and Marinecur, 1956; Gusxova
Jamvet, 1961), it is noted that
Marshallese, and cases exposed by reactor acAmano, 1953 ; Cronkite et al., 1956 ; HasTERLIs
and Barisocotov, 1956; Anprews et al, 1961 ;
all these cases similarly revealed the minimal
value at about one monthafter exposure.
od
5.
Bone Marrow
The bone marrow was aplastic at the critical stage in severe cases, which
showed remaining and proliferation of plasma cells and reticulum cells. Figure
3 shows the bone marrowof oneof the severe cases. Comparing with normal
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Bone marrowof one of severe cases at 5th week.
bone marrow a lack of bone marrow cells was observed. With the beginning of recovery, aplastic marrow changed to hypoplastic and then turned
into a type of maturation arrest.
In some cases, recovery was not complete
In less severe cases, the bone marrow was not aplastic
Several morphological abnormalities were observed: nuclear debris of
lymphocytes, binucleated lymphocytes, vacuoles of neutrophils, toxic granulations
of neutrophils, degenerative changes of bloodcells, mitotic abnormalities of
erythroblasts, ete.
Motility and phagocytosis of neutrophils decreased remarkably. After one
year, in some cases these functions were still lower than in normal persons.
FOLLOW-UP STUDIES
As above mentioned 16 to 18 fishermen have been examined on an annual basis.
Figure 4 shows the changes of the cumulative distribution curves of leuko-
int
'"
Fig. 3 Changes ar
table btm
Morphological and Functional Changes
oytes neutrophils
scbyge.y* albeciowiurnntiee | anor eR
but hypoplastic or in a type of maturation arrest even at the critical stage.
6.
am
even after one year.
cvtes. The curve of critical stage appeared clisplaced far to the left of the
normal curve. and gradually approached normal values.
of normal Japan
the curve 4ppr
in the curoulatis
However !
the changes of
are representat
A small ia
of erythroblas
10 yeats-
Cytogene
results are SU
1. The
fetta
However, the curve of the 6th year wasstill displaced slightly to the left