53
HEMATOLOGIC OBSERVATIONS
fall to reach a low of approximately 60 percent
of control Jevels at the end of the 4th week.
The value then returned to approximately the
control level at the start of the 7th week, following which a second depression was noted.
The platelet counts were at a level of 80 percent
of the control value at the time of the last observation during the 8th post-exposure week.
dividuals, Group I, rose from very lowlevels
observed on day 3 to values approximating 35
percent of control during the second week,
where it remained from the 3d to the Sth
week (Fig. +7). The counts then decreased
GROUP A-AGE <
Monocytes and Eosinophiles, All Groups
CONTROLS GROUP
Table 4.7.—Group II Ailinginae Mean Blood
Counts at Time of Maximum Depression
Age Less Than 5
w.p.c. Plates
Case No.
from Day
Neutra
Lympho
Platelets
Neutro-
L
(Average
(Average
(Average
9, 750
8, 350
4, 570
215
185
180
3, 470
5, 600
3,520 | 4, 350
2, 350
2, 070
Age 6 to 15
48
6, 220
33
$1
6, 170
4, 700
210
240
240
2,970
3, 150
3, 700
2, 500
2, 320 | 2, 150
Age Greater Than 15
1
16
28
29
ol
|
45
50
|
|
51
a9
Ld
Prey
3
wien a
—_
i
70
175
195
3,570
2,200
5, 120
110
3, 050
6, 270
6, 750
5, 650
4]
43
6, 170
4, 670
|
|
|
|
115
115
145
6, 150
215
7, 750
170
5, 650
7, 050
12, 400
5, 070
2, 370
2, 270
3,720
4, 100
2,950
2, 270
2, 220
2,450
3, 700
2, 000
2, 270
180
95
4,170
3,970
4,620
2,950
105
8, 120
3, 670
185
1, 470
2, 900
3,000 1, 750
|
16
24
32
40
46
POST EXPOSURE DAY
56
Fictre 4.7.—Serial eosinophile counts on those Icss
than and greater than 5 years of age of Group I
(Rongelap).
ho-
auto si) foraDay thomDay fom Day
6
8
44
-AGE >
ub
From Table 4.2 it is seen that the mean monoeyte count for Group I rose abruptly from an
early value belowcontrol levels to a well-defined
peak on day 12, following whichit fluctuated at
values below the control level for the duration
of the observationperiod. A similar time trend .
was noted in Groups IT and IIT,
EOSINOPHILES x 10°
4.35
The eosinophile count in the older age in-
(p>0.01) and remained at a value approximately 15 percent of control throughout the
remainder of the study. The time trend of response wassimilar in the younger age individuals, however changes in the youngerage group
were relatively greater if considered in terms
of the control values. Similar trends in
eosinophile count were not evident in other exposure groups.
It is possible that the rise in eosinophiles
represents that reported by Minot and Spurling
(11) as occurring “
two to three weeks after
short wavelength irradiation”.
4.36
Hematocrit, All Groups
The hematocrit values forall exposed groups
are shownin Table 4.8. When hematocrits were
first done on the 22d day, mean values for
Giroups [ and II were belowthose of the control
population. <A significant trend in values after
this time could not be detected statistically.