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April 27, 1964
Herbert N. Hultgren, M.D.
Stanford Medical
Center
300 Pasteur Drive
‘
Palo Alto, California
Dear Herb,
It was a pleasure to read the manuseript of your new paper,
"Farther Studies of High Altitude Pulmonary Rdema". It is an
excellent presentation and together with your first paper will
be a highly significant contribution.
I have very little to offer in the
of suggestion or
criticism, because you have done a very
Rough and convinaing
gob in presenting your conolusions and supF ting evidence,
e only question I would raise concerns Item "b" on page 13,
which does not seem entirely clear. It suggests to me that
‘there is an elevation in plasma v&lume at
.
high altitude, whereas |
we
know that in both fully. acclimatised natives and in per=
song undergoing acclimatization, plasma volume as determined
with both radioiron and radiophosphorns, is :@n
slightix lower at 15,000 ft. than at sea lev
the average
My recent data
for 17,000 fte show a substantially lower plasma volume,
I
kk the liberty of asking Howard Parker to look over
the mafisoript because he is deeply concerned with the problem,
and I thought you might like to
have his comments. I mene
Closing a copy of his comments on the papers
Both Howard and I would like to have reprints of this
and your first paper when they are available and would appreciate
being placed on your distribution list. ,
We are also looking
forward with great interest to the
are weet
studies you are under
this summer in Peru, If you con= —
taet the group in the Institute of Andean Biology. please give’ my warmest regards to Dr.'s Hurtado, Pison, and e Raynafarjes
‘
Wetze
“ONle.
.
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id
OS ne TEEGP
Sincerely,
T COPY AVAILABLE
3008255
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WYansirz
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