a
70
tlematological
T. KUMATORE
72-h culture:
No. of
cases
examined
No. of
cells
analyzed
Aneuploid
cells %
10
693
2. 88
Fishermen
13
881
2. 05
Fishermen
15
1102
2.90
16
1248
2. 48
Fishermen
10
750
2.27
Fishermen
12
950
2. 00
Cases
Control
l abne
and morphologica
were €
tions of recovery
Chromosome abnormalities in peripheral lymphocytes of the fishermen,
data from 1965 to 1967.
.
1965
1966
Fishermen
1967
Stable
cells %
(/)*
0.14
unstable
cells %
(/)*
0.14
(1,10)
(1/10)
(9/13)
(3/13)
2. 28
3, 45
(14/15)
2. 88
(15/16)
0. 46
0. 45
(5/15)
0. 56
(6/16)
48-b culture:
1966
1967
1.20
0. 67
(6/10)
(4/iG)
(9/12)
(6/12)
2.11
0.74
* Numberof cases showing the abnormal cells per total number of cases examined.
ween
Table 2
nerat
first signs of rege
g
llowin
posure, with fo
The hematologic:
ed s
1954 were report
ki:
ea
sp
Generally
the
dose soon after
dec
sons should be
is |
findings. From th
era}
to decide the th
pa
Ja
e
th
As to
tect
necessary to de
tc
ma
observed in he
so high (Table 2).
2.
Unstable abnormalities such as dicentrics, etc. were observed (Table 2).
3. The frequency of stable abnormalities was remarkably higher than
in controls (Table 2).
4. The detailed analysis of stable cells revealed that stable abnormalities
were divided following 3 types:
a, stable cells with balanced chromosomeconstitution ...67 per cent
b.
stable cells with deletionof a chromosome... 29 per cent
c. stable cells with excessive chromosome material...4 per cent
5. In 3 cases small chromosomes which are similar to the Ph! chromosome were found.
6. The examined fishermen wereclassified in3 groups according to the
degree of the injuries indicated by the minimum values of neutrophils
shown shortly after the exposure. It was found that the mean valuesof stable
and of unstable cells were higher in proportion to the extent of theinitial
damage. Minimum values of neutrophils roughly correspondedto the estimated external radiation dose.
7. Chromosome abnormalities in bone marrow were observed in 5 cases.
All of these abnormalities were limited to stable abnormalities. While stable
cells in the peripheral lymphocytes showed various karyotypes of their own,
these in the bone marrow were limited to only a few karyotypes.
Anprews, G. A»
Diagnosis 4
Organizatior
Cronkite, E-P.
Ionizing Ra
Washingtot
Cusxova, A.K
Conferenct
New York.
Hastertik, R.
Conferenc
New Yor}
HEMPELMAN, ~
Medicine
IsHIHARA, T- |
IsHtHARA, TNorth H
IsHiHARA, T242.
Janet, H.
SPERMATOGENESIS
>
World
AS a generative tissue, spermatogenesis has manysimilarities with hematopoiesis. Therefore, the changes of number of spermatozoa is described for
reference. The number of spermatozoa decreased, and minimum numbers were
obtained in 16 cases about 8 monthsafter the exposure.
Amano, S. (1953) =
Gakujutsu S
Lowering of mobility
Kixucut, T-stitute
Kutura, K-
Influer
the Pr