the Pacific has permitted biologists to develop rew techniques of investigation and his suggested other areas in which the techniques may be tested and applied. (C.H.) Descriptors: ALGAE; ANIMALS; ATOMIC EXPLOSIONS; ENVIRONMENT; FALLOUT; FISSION PRODUCTS; FOOD; NUCLEAR EXPLOSIONS; PLANKTON; PLANTS; RADIOACTIVITY; RADIOBIOLOGY; SEA i Subject Codes (NSA): BIOLOGY AND MEDICINE 10/5/179 153665 (Item 179 from file: 109) NSA-15-010726 ‘ AN ATTEMPT TO QUANTIFY SOME CLINICAL CRITERIA OF AGING Conard, RvA. Brookhaven National Lab., Upton, N.Y. Journal of Gerontology (U.S.) v 15. Publication Date: Oct. 1960 358-63 p. Coden: JOGEA Secondary Report No.: BNL-4835 Note: BNL-4835 Note: 0022-1422 Journal Announcement: NSA15 Document Type: Journal Article Language: English In order to study possible premature aging effects of radiation in the people of Rongelap in the Marshall Islands, a series of measurable criteria generally associated with aging were recorded during the 1959 annual medical survey (5-year postexposure) on 42 people who had been exposed to radiation and 84 unexposed Marshallese. The criteria were chosen on the basis of ease of assessment under field conditions considering time limitation and language barrier. Some criteria were assessed on obsevation by scoring on a 0 through 4+ and percentage basis (senile skin changes, graying of hair, baldness, arcus senilis, peripheral arteriosclerosis, retinal arteriosclerosis), The other criteria were measured directly and also expressed on a percentage basis (skin looseness, skin elasticity, accommodation of the eyes, visual acuity, hearing by audiometry, blood pressure, neuromuscular function, and hand strength). A skin caliper used for measuring skin looseness and elasticity was de scribed. Since no differences were readily apparent between the exposed and unexposed people, the data were pooled and presented at this time to describe the methodology, trend of criteria changes with age, and attempt to assess biological age. Curves of the plotted data drawn by eye shohwed varying degrees of age-associated change with different criteria. The measured criteria were generally best correlated with age, particularly accommodation of the eyes, visual acuity, skin elasticity, and hand strength, although some of the observational criteria, serilis and graying of the hair, such as arcus seemed also to be fairly well correlated. A plot of the average percentage scores for individuals by age (biological age score) showed generally increasing scores with ages and less scatter than was noted with individual criteria. It is hoped that this approach may prove helpful in assessing aging in human beings and may offer a clue to possible radiation-induced aging. (auth) 10/5/180 (Item 180 from file: 147853 NSA-15-004899 FLORA OF St. John, ELASTICITY; POPULATIONS; EYES; RADIATION 9003585 Descriptors: AGING; BLOOD VESSELS; DISEASES; HATR; MAN; MEDICINE; MUSCLES; NERVOUS SYSTEM; EFFECTS; SKIN Subject Codes (NSA): BIOLOGY AND MEDICINE 109) ENIWETOK ATOLL H. Chatham Coll., Pittsburgh Pacific Sci. v 14. Publication Date: (1960) Oct. Journal Announcement: NSA15 Document Type: Journal Article Language: English Descriptors: ATOMIC EXPLOSIONS; 313-36 p. ENVIRONMENT; NUCLEAR EXPLOSIONS;

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