55
TSH concentrations were normal. For this reason,
methods were used: TBG was measured byradio-
Jects (25 Rongelap and 31 Utirik) selected as rep-
The results were comparable since the meanratio
of TBG-binding capacity (ug T4/dl) to TBG
TBG-binding capacities were determined in a
numberof subjects with abnormal T, values.
TBG analyses were done on sera from 56 subresentative of three groups: people with low, nor-
mal, or high plasnva T4 concentrations. Two
immunoassay (M.C. Gershengorn and J. Robbins,
unpublished observations, 1974) and TBG-binding capacity by reverse-flow paper electrophoresis.
(mg/dl) was 13.9. On the basis of one mole T,
Table 31
Total and Free Thyroxine, Thyroxine-Binding Globulin, and Thyrotropin Levels in Marshallese
Subject No.
TBG,pe/dl
Ts, pg/dl
Subjects with TBG-bind capacity <14 ug T4/dl
827
917
981
2015
2126
2144
2174
2193
2220
2248
2185
7.6 (1.06) *
7.0 (1.20)
8.0 (0.69)
7.7
9.1
7.0
7.1
11.1(1.03)
13.7
11.9 (0.94)
-
Mean
S.D.
9.02
*+2.39
5.1
4.4
4.4
4.4
4.9
4.0
4.1
48
3.2
3.8
4.6
4.34
*0.543
Subjects with TBG-binding capacity 14 to 26 ug T4/
850
14.0 (1.04)
4.6
2135
15.5
6.1
2137
19.9 (1.37)
9.2
2212
20.1
3.0
2206
17.7
7.4
2182
14.4
5.0
2218
14.3
3.0
2221
15.6
2232
2257
2168
2136
2230
16.2 (1.54)
17.3
14.1
15.5 (1.06)
- 21.9 (1.28)
Mean
5.D.
4.8
4.8
8.8
4.2
7.7
6.1
S.D.
3.37
3.53
3.24
3.21
3.20
3.76
4.23
3.23
3.12
2.94
2.80
3.33
Free T4, ng/dl
1.72
1.55
1.43
1.41
1.57
1.50
1.73
1.55
0.998
1.12
1.29
1.44
3.08
2.94
2.90
1.84
2.77
2.92
3.04
1.42
1.79
2.67
0.92
2.05
1.46
0.912
2.6
2.1
2.6
<2.5
28
<2.5
3.6
2.42
2.94
2.72
2.15
1.45
1.16
2.57
1.14
1.66
0.885
6.0
2.0
<2.5
2.1
4.9
2.68
1.29
3.9
2.60
1.33
+1.87
+0.503
+0.597
2.01
1.53
1.22
0.872
1.88
0.991
1.81
0.903
1.54
1.19
1.32
1.80
1.42
1.43
+9.62
*TBG bv RIA, mg/ml.
11.05
+4.63
3.1
2.3
<1.0
<35.0
<2.5
<1.0
4.2
3.6
<2.5
+0.230
16.65
43.5
TSH, pU mi
0.40
*#2.58
Subjects with TBG-binding capacity > 26 pg T,/dl
2138
37.0 (1.52)
9.0
2229
35.7
5.9
891
56.1 (4.56)
12.9
911
47.6 (3.92)
13.6
2217
32.8
7.0
2256
51.8
18.2
Mean
DFT, x 104
+0.468
+0.358
<35.0
2.4
10.8
2.1
2.7
4.4