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BROOKHAVEN NATIONAL LABORATORY
ASSOCIATED UNIVERSITIES, Inc.
Rear Ne.
Class Gred Prole.s
__
UPTON, L.N.Y. 71973
TEL.
MEDICAL DEPARTMENT
YAPHANK
REFER
4-6262
*
408408
November 4, 1963
bas
Hal Hollister, Chief
REPOSITORY
WPREAR CMe Pyke
4
Technical Analysis Branch
COLLECTION Halbollister fi
U.S. Atomic Energy Commission
BOX No.
Division of Biology and Medicine
Washington 25, D.C.
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Dear Hal:
(of
I must again apologize for delay in answering your letter of
September 9.
staff,
However, I circulated your report to members of the
and it just took this long to get it back with comments.
I shall limit my remarks to Appendix E.
The
general tenor of comments,
as follows.
including my own,
run about
The impression one would derive from reading
Appendix E is at variance with what we feel should be given,
and
actually we disagree with quite a number of the statements made.
I doubt that the book by P. Alexander is the best place from which
to extract this type of information.
Our knowledge of effects of
radiation is much more precise than that indicated in the writeup.
et
A few examples might suffice.
On page 2 it is stated that
antibiotics do not increase the resistance of the animals toa
lethal dose of radiation.
It has been clearly demonstrated in
the mouse that antibiotics alone very substantially increase the
LDs 9. and we have shown in dogs that antibiotics combined with
platelet transfusions very significantly increase the dose level
at which animals can still survive.
On page 3 the impression is
given that we do not know the chain of events leading to death.
While there certainly is more to be learned, we do have a very
good idea of the chain of events leading to death... On page 7 it
says that the outcome is almost entirely dependent upon the
make~up of the individual and there is little opportunity for the
physician to influence the course of the illness.
I think this
gives a completely inaccurate impression, since there is a great
deal the physician can do to influence the course of the disease.
The statements in the last paragraph on the page simply are not
consistent with the fact, as are the statements in the first
full paragraph on page 10.
I can give a number of other examples
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