CONTENTS Page ABSTRACT ACKNOWLEDGMENTS _. . ILLUSTRATIONS . ' ' , TABLES CHAPTER 1 1.1 1.2 2.3 2.4 2.5 4.2 Gross Observations Radioactivity of Tissues and Excreta . 14 . 14 15 15 17 19 20 a1 22 INTERNAL CONTAMINATION IN ANIMALS . 3.2.3 Radiochemical Analysis of Tissues and Excreta Autoradiographs Pathology . . Egg Production in Chickens Fertility and Hatchability Studies in Chickens . Internal Radioactive Decontamination Studies in Chickens Summary and Conclusions . CHAPTER 4 4.1 INTERNAL CONTAMINATION IN HUMAN BEINGS Methods Results and Discussion 3.2.1 3.2.2 3.3 3.4 3.5 3.6 3.7 3.8 11 11 Methods . Results and Discussion 2.2.1 Beta Activity of the Urine 2.2.2 Radiochemical Analysis of the Urine: Estimate of Body Burden Route of Entry of Internal Contamination Internal Radioactive Decontamination Therapy . Summary and Conclusions . . : . . CHAPTER 3 3.1 3.2 11 Objectives . General Nature of Internal Radiation Toxicity CHAPTER 2 2.1 2.2 INTRODUCTION ENVIRONMENTAL STUDIES 22 24 24 24 25 28 30 35 35 38 39 40 Chemical and Physical Characteristics of Fallout Material Radiochemical Analysis of Food, Water, and Soil 7 40 40

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