Appendix V
Findings of Ep demiological Studies of Cancer in Irradiated Populations
(From J. Shapiro, Radiazion Protection, pp. 260-4, Harvard U. Press, Cambridge, MA,
1972)
No ot caves
Subject of study
|. Haroshima and Nagasaki A-vomb
survivors (bomb exploded 1945).
Bnil et ai.. 1962 (81)
Follow-up
tme (yrt
§-43
2. Hiroshima and Nagasaki A-bombd
survivors (women) Wanebo
etal.. 1968 (238)
V3-24
3. Hiroshima and Nagasaki A-bomb
survivors exposed prenatally
Jabion and Kato. 1970 (93)
10
4
Japanese A-bomb survivors ¢x posed
within 1400 m of detonation tdied
1950-1962). Angevine and Jabion.
17
§
Children exposed prenatally due to
abdominal x-ray to mother (exposed 1945-19S6 and died before
end of 19581. Court Brown et
Dose
(R o¢ rads)
0-20
21-80
81-320
No. of
persons”
Form of
cancer
85,070
13.184
% 695
o-4
10-39
40-89
90-199
>200
Unknown
Unexposed
vontrot
>64,500
person-rads”
Observed
Expected
In exposed
group?
if noe
exposed®
21
6
4
19)
30
20
3
s
2
s
o
2
2
73
3
2
2
23
2.3
61
|
075
Leukemia
Leukema
Leukemia
3.082
1.262
87
302
841
x30
2.458
Breast
Breast
Breast
Breast
Breast
Breast
Breast
cancer
cancer
cancer
cancer
cancer
cancer
cancer
1.292
All cancers
1.218
All cancers.
autopues
except leukemia
at
$6.8
e
10s
1964 (95)
at
349 166
Leukemia
All cancers
ai., 1960 ( 239)
6. Children exposed prenataily (born
in 1947-1954 and died betore end
of 1960) MacMahon. 1462 (240)
7
Infants who recerved irsadistion of
chest before age 6 mo. in treatment for enlarged thymus(treated
1926-1957, follow-up in 1963)
4-13
tee
77 000°
13-36
61-600
Lower dose [Thyroid
group
Tayrow (bemgnt
2.207
Leukemu
€22,226 per-
Hempeimann et al., 19> (160)
ws
60
4
6
3
107
xO
pas
14
1S
3
06
60
aad
0
0
90.
Qus
son yr al
risk i
Higher Jose
group
498
Thyroid
Thyroid (benign)
Leukemia
11E 48S per-
son yrat
tink?
3
infants wradsated rouunely with
X-fays to antenor mediastinuT
through small (4X 4 cm) port. 7
days after bisth, as “apparently
harmless and perhaps beneficial
procedure”(x-ray 1938-46. fol-
low-up 1956-58). Conte et al..
1900 (146)
9. Children treateg with x-rays to
head, neck, of chest for various
benign conditions, mainly ““en-
large” thymas and adenitis,
10-20
78-880
mostly 150
.
14a1,
inchuding 144
with enlarged
thymus
>t
<S0 14%)
(KIT
$0200 C26)
200-600 ¢33'7)
hott
Upto 23
3,872
Thyroid careinoms
Leukerma
Thyrow
Thyra (benign
ul
7
0
a
~
treated before age 16 and followed till age 23. Saenger et
al., 1960 (202)
10. Children treated before age 16 with
x-rays for entarged thymus.
pertussis, and head and neck
diseases: and died before age
23 (treated 1930-1946; followup 1940-1956). Mueray et
Not grven
ab. 1959 (241)
-
134 -
Leukemia
7
i4