38
may have some degree of growth retardation, also
show evidence of hypofunctioning glandsor glands
that are functioning at maximum capacity, based
on results of thyroid function studies (elevated
serum TSH levels or little or no response in ''"f
uptake following TSH stimulation). Oneof these
(No. 65) had a low serum thyroxine level. The
adults with thyroid nodules (Nos. 59 and 64) and
two of the children (Nos. 42 and 61) had normal
responses to TSH. Several of the studies listed in
Table 20 were performedafter subtotal thyroidectomy (Nos. 17, 21, 69, 2, and 20). The results
indicate inadequate function of the thyroid rem-
nant, even in Nos. 17, 21, and 69, who had been
Operated upon in June 1964 and had no thyroxine
replacement before September 1965. The serum
Figure 27. Thyroid uptake study
with '' I, Rongelap Island.
iodoproteinlevels (PBI less 7, [) ranged from 1.5
to 2.9 and did not differ significantly from values
in unexposed Marshallese.
Figure 28. Wrist x rays showing marked retardation ofskeletal maturation in dwarfed boy with
hypothyrodism (right, subyect No. 3, chronological age 10%2 yr) compared with younger brother
with normal osseous development (left, subject No 83, chronological age 8%2 yr).