Table 18
Correlation of Immunoelectrophoretic and Peripheral Blood Findings
With Age and Radiation Exposure!3 | D = decrease; I =increase}
Unexposed group
Exposed group
Change
Correlation
Percentdif.
Significance
Criterion
with age
with age (r value)
from unexposed
( p value)
Lymphocyte transformation
D
0.89
-— tl
0.68
Serum proteins
Total serum proteins
I
.35
-— 15
2+
Albumen
D
45
+ 15.0
01
Tota] globulins
Alpha-1
I
I
38
37
-17.1
—31.0
ol
Ol
[
[
32
75
- 60
— 18.3
Alpha-2
Beta
Gamma
Immunoglobulins
A
D
M
G
(IgA)
tIgD)
(IgM)
(IgG)
Kappalight chains
Lambdalight chains
K/L ratio
Blood findings
I
4B
— 20.0
01
.03
OL
I
I
I
[
49
.20
20
78
-17.0
— 3.0
— 40
— 80
05
98
74
22.
I
Al
+ 04
a4
I
I
96
24
— 3.0
— 14.0
69
15
Hematocrit
D
57
+ 29
07
Total leukocytes
Lymphocvtes
Neutrophils
Platelets
D
D
I
D
45
91
44
65
—
—
—
39
31
0+
O04
Sedimentation rate
I
72
+11.4
25
0.1
13.8
84
08
Table 19
Serum Proteins, 1973-1974
Group
Rongelap
Ailingnae
Utirik
Unexposed
Total protein
7.760.70
7.99051
7,600.50
— 7.60%0.71
Albumen
Alpha 1
Alpha 2
Beta
Gamma
Total globulin
4.224050
4.30+0.37
4.294043
4.1140.45
0.2020.05
0.19+0.07
0.16+0.06
0.190.06
0.69+0.12
0.72+0.15
0.69%0.30
0.750.14
1.082%0.24
1.05%0.20
0,890.23
1.00%0.24
1.59+0.41
1.76+0.38
1.670.45
1.5720.48
3 54270 58
3.60 = 0.56
3.330.350
3.520.354
podiploid levels were related also to radiation;
this was more pronounced in the males, with the
exposed having 2.8 times as many hypodiploid
cells as the unexposed, whereas the exposed females had 1.3 times as many as the unexposed.
Polyploid levels were not found to be related to
radiation. Both sex and chromosomesize appeared asfactors possibly related to hypodiploid
levels. In all subjects, regardless of sex or exposure,
the largest and most frequent loss of chromosomes
was in the G(Y) group (2.3 times expected loss). In
the C(X) group, females lost 15.2% more chromosomes than expected and males 12.6% less. No sex
or radiation effect was apparentin the otherfive
chromosome groups. A series of additionalcultures indicated the presence of chromosome breakage factorin the plasmaofthe exposed subjects. In
cultures of the latter, chromosome aberrations