t
Ipidini “to no}ssex4 arta “te. 9rs ‘emia yon 16 noisiess1 xbod: a ow
‘time post onset: ofuptake, days,
d
instantaneous fraction of atoms decaying per unit time, day”
~t
ao rbet
ri i
x
=
3
ee
aa
pple
p?
ett t TO%4-
rept
day~!,
initial atom ingestion ‘rate, “atoms toy
instantaneous fraction of atoma removed from compartment. i by
de Vai vidun euosne sandend
ot ee ramay Jad sina ums
snived
physiological mechanisms, day
compartment i deposition fraction,
the number, of,atdas /in“compartment i‘ relative, to the number in all
4
i
compartments at+the onset of declining continuous uptake, (t*0),
tour
gE
Pd
werd
oy.
Witob
ete bth tba a
instantaneous urine activity concentration, Bq &
uf!
-
gpalds
@eoiie!
maT Quatk
subject urine excretion rate, & day 1,
a
fraction from:Gl; FEaSt, to dloods s+, pe
fraction excreted by the urine pathway,
|
+
8G ba
|
5
st
instantaneous fraction of atoms removed or added to the atom uptake
ma.
Pray!
a
ett
7
:
(ype
ery
Yo
i?
atu
de
i
per unit time, day~*, due to dactore® ot er. than radioactive decay,
wet
ou
2
instantaneous body burden, Bq,
cat
ee
body burden at the onset of uptake, ‘Bq,
ed
utah
sey
ee
the number of disintegrations in all compartments occurring ‘during
the uptake interval, Bq days,
.
:
The development of Eqs. (1), (2), and (3) was based on the following convolution integral.
At some variable time, T, defined during a fixed uptake
interval, T, the daily activity ingestion rate crossing the gastrointestinal
tract to blood is given by
ures
“4
SOM
o
e
~(ketdr) Tt
e
aya ee Re heats Preeoy!
rote
Pete.
AEP