BNL 3372
Tis WIATOLCTY CF YONTTING RANIATICN
B.P.
8.1
Cronkite,
V.P.
Bond,
ond
RA.
Conard
Scope and Status.
The advent of the atomic cra has boson a great stimulus to research in
the field of hematolecy.
This dis quite undesstandable because changes in the
blood and blood-forming organs, imperfect indices thoush they may be, still remain
the moct sensitive biological evidences for excessive exposure to penetrating
zonizine radiations.
With this chapter will be considered the more comuon changes
that are induced within blood and blood-forming organs by acute and chronic exposure to ionising radiations.
Early Reports.
early part of this century.
These chanzcs nuove been studied extensively since the
Despite this
-
8.1.1.
a diverse mass of data exists in tke
describe and measure adequately the doszse of
there are many conflicting reports.
ey
literature, arising prinarily from the inability of the carly investigators to
onising radiation; accordingly,
Mowover, the osiginal rcports of Meinecke,
1905-5, remain qualitatively corrects as docs the excellent report on blood chenges
in paticnts undergoing therapeutic isradiation (Minot and Spurlinc).
An excclient
analytic review up to 1942 is that of Dumlan in Warsen’s general review.
Since
then there have been various generci dissertctioas on the relation of hematopoiesis
to the effects of ionizing radiation (Lawrence, et al., and Osgood).
8.2
.
In addition to the disccepancies ia dosage measurements, the differences
in specics sensitivity and sesponse were not cyopreciated until
a
+
Of P particular importance
is the fact that many
?
’ investisators
o
au
Ci
on
Cause of Discrepancies in Data.
the last two decades.
were notaware of tho
differonce between
the pictures produced by unifera tetalebody exposure, unequal”
wee
Aedes
total-body exposure, and that produced by paortiaiebody
exposure.
Complete or