-7- UCRL- 3644 Advantages Minus Cost Equals Net Gain The sum of evidence would lead to the conclusion that radiation probably does affect man's health subtly, and--like money and time--it should be exchanged for equivalent advantages. Since the usefulness of atomic energy--including material and energy gain and defense measures of prime importance--is a positive result, and the radiation effect upon humans generally is a negative result of the atomic age, atomic energy usefulness minus harmful radiation effect must be equated to the net gain. Therefore it is critically important to estimate hazard quantitatively, and to be mindful of other factors while doing so. However, there is no una- nimity of opinion at this time as to the precise balance that should be achieved between advantages and disadvantages of use of atomic energy, because certain qualifying factors are still too poorly known. Uncertainties exist which can mean either underestimation or overestimation of the effect of radiation. This brief synopsis roughly appraises the biological costs of exposure to radiation and presents information which must largely guide decisions in the interim until more precise information on radiation effect is available. A summary of current knowledge of radiation tolerance or hazard and fallout is provided in several major public documents that have appeared in 2 34,5, 6 1956 in broad survey of the problems to man of atomic radiation and fallout.” , The Concept of Maximum Permissible Dose Karly estimates of that amount of exposure to ionizing radiation which constitutes a permissible occupational hazard placed the upper limit at 0.lr per day. Such a value was exceedingly conservative in view of information available at the time it was established. It is lower by a factor of 50 than chronic exposures leading to physiological disturbances and radiation sickness, and by a factor of 1000 to 5000 than the dose which, in a single exposure, might threaten life. Also, at the time it was proposed, 0.1 r was the lower limit of radiation exposure dose knownto elicit any biological response. Evidence on the magnitude of physiologic response of the individual to radiation in the range 2 ; ; National Academy of Science,''The Biological Effects of Atomic Radiation - Summary Report," 1956. 3 ; National Academy of Science ''The Biological Effects of Atomic Radiation - Report to the Public," 1956. t British Report, "Radiation Hazards to Man,'' Cmd 9780. Bar: . Willard F. Libby, "Current Research Findings on Radioactive Fallout}! Proc. Nat. Academy, Dec. 1956. 6 M. Eisenbud and J. H. Harley, 'Radioactive Fallout Through September 1955,'"' Science 124, 3215 (August 10, 1956).

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