in mice as a result of expagyre to a dry-particle simulant incorporating
2eday old fission material,The simulant employed was composed of
tracer amounts of fission»pxoduct chlorides adsorbed completely on dirt
particles in a wide size range, The simulant was gene rated‘as airborne
The
simulant is, however, notémecessarily of the samechemical form as
fallout which would tend torgpeximize the hazard as approximated here,
Earlier studies have tras A the fate of two other types of ajmulanta—
anionic simplant* and a
ft slurry simulant,? The former’ ‘épresé ts
the falloutithat might oce
Mowing a nuclear de chation in’aes water,
and the latter a detonationiin ‘a shallow harbor, The biological response
to anexpogure to fallout i Adependent on the "properties of thée?carrier
material, The results ob
Hedwith the drysparticle simulant in the’
typea of aimulants prod
ie previous studies,’
’other
copipayed with results obtained witH
present experiment wereuced
i
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In orde stp assess the ‘¥al ; tive importance”of inhalation and ingestion
‘as modes
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for theMaspion products in sti Body, thaede particle
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The simulant was prepared from neutroneirradjated uranjum obtained
from the Materials Testigg‘Reacitor, ° The mixture of fissiot-products
was dissolved in JIG) and qdded to a solution of previously prepared dirt
particles of Ambrose clay loam of less than’40 microns in diameter,®:
The partig}g -fisssion-progugt mixture was eyaporated to dryness ina
ball mill fo insure mixing, The resultant s{mulant consisted'of dirt
particles With an average giameter of from'] to 5 microns With the
fission products adsorbedon the surfaces. ‘The solubility of’ the activity
adsorbed on the clay part{gles was 8 per cent in'water and18'percent
in HCl at pH = |, The aniti@ls were exposed'to this simulant within 2_
after the removal ofthe irradiated uranium from the reactor,
days
ree
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Preparation of (heSimulans.
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mode of a f hinistration wa at
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encountered as a consequenge of a land-based nuclear detonation.
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particulates and representa,qualitatively, the fallout which’ tight be | ''
UNCHLASSIFLED