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Table 26
Kinetic Analysis of !321- Accumulation and Excretion in Rongetap Subjects Without Thyroid Abnormality
Fraction of extrathyroid I- per day
Urine* A6)
Thvroid** Ag,
Thyroid fraction,
Aai/(Az1 + Aes)
0.81 (0.17-1.99)
1.10 (0.34-2.57)
0.79 (0,23-1.47)
0.67 (0.33-1.27)
0.49 (0.26-0.77)
0.38 (0.24-0.65)
1.18 (0.72-1.49)
0.90 (0.57~-2.06)
0.43 (0.19-0.58)
Group
& Unexposed adults, 1965
12 Exposed adults, 1965
12 People exposed at
age 10-20. 1972
*\ei is the fraction of iodide outside the thyroid excreted in the urine per day.
**\., is the fraction of iodide outside the thyroid that enters the thyroid per day. Means andranges given.
Table 27
Results of Follow-Up Evaluation of Plasma Thyroxine and TSH in Marshallese With Known Thyroid Lesions
(Normal values: T, by RIA, 5.0 to 10.2 pg/dl; TSH, <1 to 3 wU/ml; abnormalvaluesare given in boldface)
1972
Subject No.
and sex
Age at
exposure
Diagnosis
T4,
pe/dl
1973
1974
TSH,
pU/ml
Ty,
pg/dl
TSH,
pU/ml
79
6.8
8.2
0
7.4
-
376
-
1.8
> 120
Ts,
TSH,
pg/dl pU/ml
TBG-binding
capacity,
pe T./dl
Rongelap exposed
2 M
17 F
19 Nf
21 F
42F
23 Mf
69 F
72 F
15 F
20 M
36 M
61 F
73F
18 F
40 MI
64 F
1
1
2
"
3
3
3
3
4
4
6
7
7
7
8
12
21
29
30
Ailingnae exposed
8F
1
33 F
8
51 F
29
45 F
32
41M
44
In utero exposed
83 M
2ndtn
Curik exposed
2208 F
35
2212 F
35
2229 F
20
27271 F
54
2.5
3.7
6.5
,
"
"
"
"
"
"
Carcinoma
Adenomas
"
"
"
"
Carcinoma
Adenomas
Carcinoma
Adenomas
Nodule 0.5 cm ’73; neg. °74
Adenomas
"
Nodule left lobe
-
149
-
<2.5
-
23.2
13.4
126
158
2.8
98
<10
77
7.0
10.0
12.4
0.4
7.2
7.6
2.0
3.4
<2.5
<2.5
81
<25
460
9.2
2.7
<2.5
6.4
110
2.5
172
13.1
3.6
11.9
10.1
5.1
6.6
0
11.3
13.9
25
4.1
22.7
17.8
7.8
10.6
32
62
149
59
-
7.8
7.1
5.6
2.0
2.6
2.7
12.1
7.4
6.3
4.6
4.5
Adenomas
Adenomas
i
Carcinoma(follicular)
Adenoma
15.3
6.7
10.1
2.5
oe
3.1
11
-
5.1
5.0
5.9
4.9
3.6
10.1
L.7
-
1.7
32
118
-
13.8
69
12.8
17.4
7.8
ill
<0.4
98
8.9
1.3
4.6
23
10.9
7.8
9.0
<1.0
<1.0
1.1
<10
6.3
il
116
<1.0
<1.0
15
2.8
5.6
<1.0
2.6
1.2
4,9
<5.0
14.0
94
6.9
4.6
6.0
<1.0
<10
3.9
1.7
4.4
13.3
-
6.2
7.0
12.9
70
4.4
5.5
° 3.6
<10
9.8
1.4
54
16.3
20.1
35.7
15.6
<5.0
<2.5
<5.0
20.4
26,2
17.4
45.5
25.3
roms
65 F
"
Adenomas
It
——
1
1
1
ne
a
7
3M
33 F
34 M