DOCUMENT SOURCE
Lawrence Berkeley Laboratory
Archives and Records Office
RECORDS SERIES TITLE
Applied Science Division:
Scientists’ Papers - Papers
of William E. Siri
ACCESSION NO.
434-91-0131
FILE CODE No
19-14-18
CARTON NO.
7
FOLDER NAME
——
,
COPY
Or. Leo Meyer (Marshall Islan
d Natives)
NOTES
FOUND BY
Peny Hail
Aad ed
November 30, 1962
Leo 4M. Meyer, M.D.
south Nassau Communities Vospital
Ouu5 Oceanside Road
Oceanside, New York
Dear Leo,
“ere is the procedure on the use of tritiated water for
measuring total body water,
1.
We will provide the HTO.
Let me know by return mail if we
should send it to you and where, or if you will pick it up when
you pass through San Francisco.
2.
Give by youth 1 ec of HTO,
‘Transfer from stock bottle to
a glass, cup, or beaker exactly 1.00 cc HTO with a tuberculin
syringe (or 1 ce pipette).
Add 50-100 ce water and have sub
ject drink entire contents.
Add another 50-100 cc water to the
vessel and again have subject drink entire contents.
3.
‘Tritium dilution can be determined in either plasma or urine
Cor both).
Tf urine samples are collected, follow this procedure:
(a)
‘lave subject void about + hrs. after taking tritium. (b)
Take 10 ce urine samples at approximately 5 hrs., 8 hrs., and
12 hrs. after taking tritium.
can be obtained,
A 24 hr, sample is useful if tt
Put the urine sample in a 3 or 5 dram vial
with a erystal of thymol and labeled with name or code number,
date and” time after administration of HTO.
If a plasma sample is taken (in addition to or instead of
urine), "ke the sample 4+ to 6 hrs. after giving the tritium.