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Having this background notice that human lung tissue has a well
known carcinogenic potential under a number of situations, including
exposure to jonizing radiations; and that in the Hanrord dog study induction
of lung cancer was observed after exposure to plutonium aerosols.
These
are a sufficient basis to establish plutonium induced lung cancer as a_
legitimate concern for humans.
The following is a review of the official guidance for estimating
the carcinogenic effects from exposure to radioactive particulates.
‘1.
"(210} The NCRP has arbitrarily used 10% of the
volume of the organ es the significant volume for
irradiation of tne gonads. There are some cases in
which choice of a significant volume or area is
virtually meaningless. For example, if a single
particle of radioactive material fixed In either lung
or lymon noce may be carcinocenic, ine averacaing or
dese either over tee lura, nr one cubic centimeter
may have |titile to do witn the cacc.. Use of siantficant
volumes or Zreas must be looxed on as one of the round
off devices which in special cases must give way to
detailed study.”
NCRP Report #39
Basic Radiation Protection Criteria
January 15, 1971.
(emphasis added)
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