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APPIDIn "3" (colT'p)
APPEVDIX 3.2.4.5 (Cont'd)
many technical problems that such a study entails.
Personal communication, Dr. Cronkite
AP:ENDIX 3.2.5.2
"Some of the recent work being done in Dr. Howland's Division on antibiotics suggest that they may be of considerable use
{in therapy).
If this is confirmed by subsequent work s proposal
alonz those lines could be submitted lator.’ t
University of Rochester
Letter of Henry A. Blair
APPENDIX 3.2.5.3
Therapcutic studics provosed by the NMS are of a very limited
character, and as planned at present do not involve a large sorics
of animals (perhaps 20).
The attitude of the MME is similar to
that adopted in I'r. Blair's letter: "lo suggestions are made to
expose animals for studies of penetrating radiation (as regards
therapy) because it does not seom likely that they could add anything to the results of work done under contralled laboratory conditions,
There is one possible exception to this in the field of
thorapys reese”
Personal communication, Capt. Dracoger
APPELJIX 3.5.1
"If it wero docided to study mammalian fenetic effects, it
might be necessary to expose a fow more animals
(than the ones
for acute Icthality, otc. sec: 3.2.1.2) fomales.... providad it
appeared mandatory to brecd oxposed females.
This would be to
avoid complicating longevity studies on surviving females through
suncrimposition of obstetrical and post-partum fatnlitics on the
data,
There appears to be no good reason why the surviving males
could not be used both for breeding and longevity studics.
....the
mammals should be bred as soon after oxposure ns possible to determine the porcentage and types of mutation, and then bred later to
detcrmine racovery, if any with subsequent maturation of germ ecclls.
University of Chicago
Proposal of Dr. Franklin C. McLean
APPEMDIXCIS :
3.2.44,5
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