a
APPENDIZ "3"
APPE"DIXES 3.2.4.1; 3.2.4.6; 3.2.4.4
See attached drawing of tanks for exposure of vigs and otner
animals.
It is planned that teams of pathologists from the Naval
“edical Research Institute and the Army Medical School will be on
hand to perform seriai autopies at the earliest time possible after
the blast to obtain tissues for histoligic study.
At the same time,
tissues would be quick frozen for transmission to the Army ledical
School where studies of various enzyme systems, and histochemical
studies would be conducted.
The freezing method contemplated is a snecial deep freeze
chamber containing ¢ry ice.
Air transportation to Washinston would
be provided.
See also 3.2.4.3, following.
Personal Communications,
Colonel William Stone, If. C.
APPENDIX 5.2.4.5
"Dr. Doherty suggests an experiment on the effects of bomb
blast on enzymesinvitro and invioo.
His proposed experiment
would be concerned with prompt isolation of enzyme systems from
irradiated animals and determination of activity changes. Purified
enzyme systems invitro would be exposed and the effects determined
at once."
Equipment list included.
Oak Ridge National Laboratory
Letter of Alexander Hollacnder
APPLIDIX 3.2.4.5
It is intended that this study will consist of:
a) Study of vascular and other changes in
methological
preparations obtained thr ughout the radiation experiment and
studied in the U.5.; and
b})
Studies of the chemical constituents of the clotting
mechanism in plasma frozen on the spot and transported to the
Neval Medical Research Institute for assay.
This procedure is proposed because of the claborate equinmen’
needed for detailed studies of blood clotting; and because of too
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