-~4. CABINET PAPER—PRIVILEGED Property of the White House—For Authorized Persons Only 9. If one assumes a direct linear relation between biological effect and the amount of dose, it then becomes possible to relate very low dose to an assumed biological effect even though it is not detectable. It is generally agreed that the effect that may actually occur will not exceed the amount predicted by this assumption. Basic Biological Assumptions Because there are insufficient data to provide a firm basis for a “ts especially because there is great uncertainty on the biological effects at very low doses and low dose rates, it is prudent to use these conservative assumptions in providing radiation protection guides. 1, There is no point below which exposure to radiation will not have a biological effect. 2. There is a linear relation between biological effect and the amount of radiation dose extending down to zero. These assumptions are indeed conservative and somewhat arbitrary. It is important that additional research be undertaken and new data developed to provide a firmer basis for evaluating biological risk. Appropriate member agencies of the Federal Radiation Counci are sponsoring and encouraging research in these areas. Recommendations It is recommended that: 1. There should not be any man-made radiation exposure without the expectation of benefit resulting from such exposure. Activities resulting in man-made radiation exposure should be authorized for useful applications provided the recommendations set forth herein are followed. CABINET PAPER For Consideration