eerad

30

types.°7 For the three major pathogens found, the

overall infection rates were: Entamoeba histolytica,
18.2%; hookworm, 5.5%; and Trichuris trichwra,

34.3%.

Eosinophilia (>>5%) has consistently been noted
in about half the people. The fact that half the
cases with eosinophilia showed no helminthic infections at all suggests that other factors besides
parasitic infections must be responsible. The
eosinophilia may be related to chronic fungus and
other infections, particularly of the skin.
Complementfixation studies for parainfluenza1, 2,

and3, respiratory syncitial, psittacosis, and Qfever
showed antibodiesto all groups of viruses except
that for Asian influenza, which probably had not
yet seriously involved the people of the Marshall
Islands. The antibodytiters appeared to be somewhatlowerin the exposed people.
Immunoelectrophoretic analysis showed neither a
paraproteinemia nora typical picture of antibedydeficiency syndrome, but a high frequencyof increases of someof the immunoglobulins was noted.
Blood volume studies with 51Cr-labeled sodium
chromate showeda significant reduction in red
cell mass and/or plasma volume. However, there
is some indication that Americansliving in the
Islands for more than 1 year mayalso haveslightly
lowered values. Tritiated water has been used to
establish the relationship of blood volumeto lean
body mass.

Acknowledgments
The cooperation of many agencies and persons
was necessary to carry out these surveys successfully. The authors are deeply grateful for valuable
assistance to many individuals too numerous to
name. Weare particularly grateful to the people
of Rongelap and Utirik Atolls for their cooperation in these examinations.
Manyofficials of the Atomic Energy Commission, particularly Dr. John R. Totter and Dr.
H.D. Bruner and their staff of the Division of
Biology and Medicine, and Mr. W.A. Bonnet and
Mr. W.Streenan of the Honolulu Operations Office, were most helpful in coordination of arrangements and in supporting the surveys in every way
possible.

Weare gratefulto the officials of the Department of the Interior, particularly Mrs. Ruth Van
Cleeve and Mrs. Elizabeth Farrington, and the

9006301

officials of the Trust Territory of the Pacific Islands, including High Commissioners Mr. E.E.

Johnston and Mr. W.R. Norwood; the Director of
Medical Services, Dr. W.M. Peck; the District Administrator for the Marshall Islands, Mr. Robert

Law; the Director of the Majuro Hospital, Dr.
John laman, and members ofhis staff; the Trust
Territory Representative at Kwajalein, Mr. W.M.
Ownby, and Dr. Ezra Riklon at the Ebeye Hospital; all were most helpful.
The Pacific Missile Range Facility at Kwajalein
was of great assistance in furnishing necessary airlifts and materials. Mr. Frank Granich andothers
of Global Associates at Kwajalein, Dr. Y¥.C. Smith
at the Kwajalein Hospital, and Colonel D.B. Milar,
Commanding Officer, were extremely helpful.
At Brookhaven National Laboratory, contributions were made by manyindividuals in many departments, including Medical, Instrumentation
and Health Physics, Photography and Graphic
Arts, the Shipping Section, and others. We are
grateful to the following people at BNL for their
support and advice: Dr. Maurice Goldhaber, Director; Dr. V.P. Bond, Associate Director; Dr.

J.B.H. Kuper, Chairman of the Instrumentation
and Health Physics Department; Dr. E.P. Cronkite, Chairman of the Medical Department, and
others in his Department, including Drs. D.D.
Van Slyke, J.S. Robertson, and S. Cohn, and
Messrs. A. Finn, G. Jackson, and W. J. Walsh. We
appreciate the assistancein statistical analyses
given by Mr. Keith-Thompson.
In regard to advice and consultation on the thyroid pathology in the Marshallese, we are indebted to Drs. S. Warren and W.A. Meissner of
the New England Deaconess Hospital; Dr. B.P.
Colcock, Lahey Clinic; and Drs. L.K. Dahl, H.L.

Atkins, and H.A. Johnson of Brookhaven National
Laboratory. We are particularly grateful to the
nursing staff here for their kindness and excellent °
care given the Marshallese thyroid cases.
Wewishalso to thank Mrs. J. Redzinak for her
devotedsecretarial assistance, and Mrs. M. Dienes

for her editorial help.

References
1. Cronnire, E.P. er av., The Effects of Ionizing Radiatwn
on Human Beings: A Report on the Marshallese and Amencans Accidentally Exposed to Radiation Fallout and a Dtscussion ofRadiation Injury in the Human Being, AEC-TID

9358, U.S. GovernmentPrinting Office, Washington,
D.C., 1956.

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