i8 T } T Ty TT vr T T T T T Ty T 50— T FEMALES 40 LIMITS £15S.E. 40r| FEMALES 30- LIMITS # 1S.£. a - ad _—, 20 ” 2 Hf ° 40rE Po Le le CONTROLS 4 20/-— — a 2 by ta fl ry : 2 MALES 7 LIMITS £ 35.6. 7 _ 30/- o a’ 54 4 10;-- 0 eii’?s Le Zz oF | 30;- 1 uw “ co at. 50 0 Of 4 =~“ L i i } 1 I £ L L | t L Ll 1 z ‘_ 40 MALES LIMITS £ 1S-.E. 30 7 4 _ CONTROLS 4 2 | 3 ete 10 200 ot dt tt 8:té«'D so.08—C tl tl 60—‘é27710D —_ 10 AGE AT EXAM (yrs) 20 30 40 50 AGE AT EXAM (yrs) 69 70 Figure 19. Counts of subcapsularflecks (made as described in the text) averaged within each exposure group for persons of similar age. Left: Unirradiated Marshallese people. Right: People exposed to 175 rads fallout radiation in 1954. Results My Cy ™.3 cn cn a The fleck counts were analyzed separately for males and females, and, within each exposure group, were averaged for consecutive intervals of age to produce age-specific subgroups. The average fleck count andstatistical limits extending one standard errorto either side were then computed for each subgroup.(Persons over 61 years of age were omitted.) The results are shown in Figure 19 for the controls and for the irradiated individuals. Each subgroup of the latter is connected by a solid line to its presumed location on the (broken) control curve at irradiation 15 years prior to this examination. The individual fleck counts arelisted in Appendix 3. {In the nonexposed females the numberoflens flecks rose rapidly during adolescence but at a muchslowerrate thereafter. Females aged 13 to 20 years at exposure exhibited the greatest difference from their nonexposed counterparts. (Fleck counts were not obtained on persons <_15 years of age, but would likely be lower than in persons >> 15 years of age.) Females who were mature at exposure also yielded fleck counts higher than those of comparably aged nonexposed females, but the difference wasless. (Twofleck counts >150 were excluded from analysis.) Nonexposed males had fleck counts that increased with age, but in contrast to that for nonexposed females,the rise was slower and appeared to be linear with time. Males exposed to 175 rads were the smallest group, which may contribute to the erratic fleck counts obtained. Thelevels of confidence were generally low because of the nature of the examination and the numbers of persons examined. Confidence at the 95% level was found only between nonexposed majes averaging 16 years of age and (1) the oldest nonexposed male subgroup, and (2) 175-rad exposed females older than 25 years at examination. Although somefine structure has been implied, the results for each group can be represented by a straightline. Discussion The primary findingin this survey was the continuousincreasein lens flecks with age in nonexposed males and females. Whereas the increase for females was more rapid during adolescence, lens flecks in males rose at a lower but constantrate, consequently, fleck counts in males did not equal