Charles W. edington ~2- MAYALL AND CARRANO, Lawrence Livermore Laboratory Method: fhey would like to use their own techniques for measuring DNA/chromosome. It is sensitive and look promising. They'd like to use this population as a test population to work it out. They can see a two to five percent difference with age. DNA variation is indeed greater in older people, say _ in content of DNA for 4a specific chromosome. At that time they figured it would be about 18 months until their methods were ready for field atudies and that would be May 1975, Blood could be collected in: field and sent to Livermore, Chromosomes would be stained with usual systems and also with banding methods, ‘Semen samples might also be collected for study by Bart Gledhill, reproductive biologist. It is apparent that they see this as an opportunity to test some of their systems; we should not overlook this possibility, but should cértainly uee the standard methodologies first or at least, BENDER,John Hopkins This work should be done! the people should be studied before resettlement or immediately after resettlement. The slides could be made by somebody in Hawaii. Perhaps fly blood to Hawaii; slides could be made and stored for examination Later -- should be frozen, but very important thet they be kept dry. People: A professional should plan it and decide who should do it. Carrano is good. Petersen and Deaven at LASL are good. Brewen and Preston are good. BLOOM, University of Michigan, now of Columbia University A study of somatic cell aberrations is a reasonable thing to do, We need low dose effects data, and it might be obtained on these people,