be directly compared with sublished excretion rate data for estimation
of body burdens,
3.
large-volume sample.
Because of the limitations of radiochemical and
counting procedures, large-volume samples (>5000 ml) must Se collected
for bioassay of transuranic nuclides.
consist of five or more
Typically,
these samples will
ys of 1 Liter urine collections.
Special
precautions must be followed to minimize the possibility of sample con-
tamination with extraneous materiai, primarily "locai" duse and dirt.
Sample Collection and Receiving
Provide the subject with a clean 1 liter polyethylene bottle.
Instruct
him/her to empty the bladder just prior to sample collection, to wash his/her
hands Ddefore each successive voiding into the sample container and to coliect
all urine passed until the sample container is filled.
The 1 liter container may also be used for single-void samples.
Instruct
the sudject to wait until he/she has to urinate, then give instructions to wash
hands and void into the container until bladder is empty.
For larzge-volume sam-
ples provide the subject with 5 or more 1 Liter bottles, using the collection
procedure as indicated above.
The subject must collect all urine voided for cne-
next 3 - 10 days until all of the bottles are filled.
After samples are submitted to the field trip team 15 grams (1 Tablespoon)
of boric acid are added to each liter.
Large-volume samples intended for plutonium analysis must be acidified with
nN
10 ml of concentrated HNO, per liter of urine and the date noted on the bottle.