HEMATOLOGIC OBSERVATIONS fall to reach a low of approximately 60 percent of control levels at the end of the 4th week. The value then returned to approximately the control level at the start of the 7th week, fol- lowing which a second depression was noted. Theplatelet counts were at a level of 80 percent of the control value at the time of the last ob- 53 The eosinophile count in the older age in- dividuals, Group I, rose from very low levels observed on day 3 to values approximating 35 percent of control during the second week, where it remained from the 3d to the 5th week (Fig. 4.7). The counts then decreased servation during the 8th post-exposure week. AGE < Monocytes and Eosinophiles, All Groups From Table 4.2 it is seen that the mean monocyte count for Group I rose abruptly from an early value belowcontrollevels to a well-defined peak on day 12, following whichit fluctuated at values below the control level for the duration of the observation period. .\ similar time trend 1 E0SINOPHLES 210° 4.35 was noted in Groups IT and ITI. Table 4.7.—GroupII Ailinginae Mean Blood Counts at Time of Maximum Depression Age Less Than 5 w.p.c. (Average Flaine (Average Neue (Average Lympne Pisi Case No. fromDey 50 to ay | 8 8 44 | 29 31 41 43 45 50 5) 59 70 215 185 180 6,220 6,170] 4,700 ” 28 2B to %) from Day 39 to $1) 210 240 240 from Day 39 to $1) 3, 470 3,520 2,350 5, 600 4,350 2,070 2,970 3, 700 2,320 3, 150 2, 500 2,150 / 6, 170 | 4,670{ 175 195 3, 570 2, 200 2,370 2, 270 | 6, 750 5, 650 5, 120 6,150} 11S 145 110 218 4,100 2,950 3,050} 3, 700 2, 2, 2, 2, 220 450 270 000 7,050 | 7,750} 12, 400 | 5, 070 95 170 105 185 3, 970 2, 4, 620 2, 8, 120 | 3, 3,000 | 1, 900 950 670 750 | 5,650! | | 115 180 3,720 24 320640 POST EXPOSURE DAY tS Fiovre 4.7.—Serial eosinophile counts on those less than and greater than 5 ycurs of age of Group I ( Rongelap). (p>0.01) and remained at a value approximately 15 percent of control throughout the remainderof the study. The time trend of response was similar in the younger age individuals, however changes in the younger age group were relatively greater if considered in terms of the control values. Similar trends in eosinophile count were not evident in other exposure yvroups. It is possible’ that the rise in eosinophiles represents that reported by Minot and Spurling Age Greater Than 15 | 6,270 | 6 L Age 6 to 15 48 53 81 1 16 from Day 9,750 8, 350 4,570 | Ni o 2,270 4,170 1,470 (11) as occurring “—— twoto three weeks after short wavelengthirradiation”. 4.36 Hematocrit, All Groups The hematocrit values for all exposed groups are shown in Table 4.8. When hematocrits were first done on the 22d day, mean values for Groups [and II were below those of the control population. A significant trend in values after this time could not be detected statistically.