PRIVACY ACT MATERIAL REMOVED ae te % a, a AS wy ~~ hd Es tact P af Anes . ; : : mS. . re - ott . 8. One of two boys who have developed myxedema. Left, At 12 years of age at beginning of treatment with thyroid hormene. Right, Marked growth and improvement in appearance after three years 7. Papillary carcinoma demonstrating extensive connective tissue invastion within lobe. Patient had multiple cervical lymph node metastasis thematoxylin- of treatment. eosin stain. X64). raid was not demonstrated in adults with nodules or with carcinoma of the thyroid. Thyroid Lesions in Marshallese, March 1969 influence of Physiological Stress i iti on Thyroid Abnormalities An assessment was made of the relationship o the development 1 nship of of puberty to the occurrence of thy7 rod lules. NOGICS., Des < egrees oOo of pu b ‘ent escen changes have been recorded annualIv bv oa grading svstem. The two bavs that showed sreatest retarda. . tion of growth had developed atro. . : vent ; . phy oof the thyroid gland before puberty. Here changes associated with puberty were delaved. There mav be some assockition between the apparent imne¢reased demand for thyroid hormone at puberty and the JAMA, Oct 32. 1970 # Val 214, No 2 Judi; | Island Group (Radiation Age Oose-Gamma) Exposure (yr) Rongelap (175 Rad). <10 >10 Rongelap <10 Utirik <10 (6° Rad) (74 Rad) Estimates d Thyroid Dose (Rad, Radioactive todines*) §00-1.400 160¢ wee >10 710 woes ee anaes <10 lunexposed) S10 Rongelap Dose from ! 43]. 062}, May, vas. T 4 hyroid Lesions C%)t 89.5 (17 of 19) 8.8 (21 ( 3 of af 63) 34) 39.6 a 275-550 Matlinnant Lesi os (% 5.3 4l of > 5.9 (Qof in orate. 0.0¢ Oot 6) 55 12.5( _ 55-100 1 of 8) 7A Lotta 0.0¢ Gof 40) 14 .b¢ 3 0f 59) 3.0( 3af 99) (oe I 0.0( Oot 6)) “ 23( 3of 133) a 1.5 ¢ 3 of 194) a Leos 1GQabatuc. ‘Based on number nowliving. tChildren 10 to 20 years of age at exposure received doses belween 160 and $00 rad Thyroid Neoplasia—Conard et al PRIVACY ACT MATERIAL REMOVED 321