32
The various CM@trves generally associated with
physiological sengscence are known to show wide
variability among individuals of the same age, and
this was borne out by these data. However, some
of the criteria appeared to be better indices of aging than others, judging by the degree of change
and the variability of the data observed. (This
statement is not based on statistical analvsis.}
scoring of the latter. This appeared generallyto
be the case, but the estimated vatues for greving
of the hair and arcus senilis correlated surprisingly
well with age. The amount of subcutaneousfat
probably influenced measurementsof skin loose-
ness, but, since loss of subcutaneousfat is somewhat age dependent, probablyin the right direc-
Some‘of the better criterla appeared to be accom-
tion. [tis hoped that in the future statistical trearment ofthe data mayfurnish a weighting factor for
each criterion based on the degree of age-associ-
streneth. The measured criteria would be ex-
not always possible to run the complete battery of
modation of the eves, visual acuity, skin retraction,
arcus senilis, greying of the hair, and hand
pected to be more reliable than the estimated ones
in view of the subjective element and less precise
Table 20
Residual Beta Burns, 1960
Subject
No.
Sex
Age
Description
17
F
24
F
26
M
§ Slight depigmented scars, left antecubital fossae.
19 Mottled spots of pigmentation and
depigmentation, dorsum offeet.
18 Marked scarring between frst and
F
to subcutaneous tissues. Areas of lesser involvement peripheral to this
area. No evidence of chronic radiation dermatitis.
20 Slight mottied pigmentation-depig-
39
second toes, right foot, with binding
mentation with little scarring, dor-
49
F
39
F
63
F
67
78
F
F
sum of feet. Mottied hyperpigmented spots persist on back of neck.
21 Black moles believed to have increased in number overright side of
neck, also several noted in left antecubital fossa.
40 Mottled roughening and pigment
variation, back of neck.
ated change and the variability of the data. [tis
tests on each individual, and use of such weighting
factors would tend to minimize the disparity due
to the omissions.
The data presented must be considered aspreliminary in nature and to represent only a small
fraction of the many varied changesassociated
with the agtng process. Under the conditions of
examinations of the Marshallese, the battery of
tests employed is necessarily limited. As more ex-
perience is gained, some of the tests may be eliminated and new ones added. The tests of vigorare
thought to be extremely important in assessjng
aging, and it is hoped that moretests of this nature
may be added. At this time the data are presented
to introduce an approach to a feasible means of
assaying “biological age” which might be of use in
studying the possible effects of radiation on the ag-
ing phenomenon in human beings. In the case of
the exposed Marshallese, results of further aging
surveys will be carefully evaluated, and the results
42 Mottled pigmentation, left side of
neck, with slight roughening ofskin.
20 Depigmented scarred areas with
slight atrophy of skin over dorsum of
feet, particularly at site of deeper
scar on left foot. Some areas adjacent
to scars show increased pigmentation.
ON
43 Pigmented moles appear to have iny
creased in number over left side of
M
1185982
Figure 32. Residual scarring between first and second
toes, right foot, fram beta burns, 5 years post exposure
(Subject = 26).
ao
79
neck and to lesser extent on right
side at sites of rather deep beta
burns.
45 Back of left ear shows depigmented
scar with some binding down to cartilage. No evidence of breakdown.