PRIVACY ACT MATERIAL REMOVED 39 row examinations will be carried out in both these Sene Merrow Examinations The differential counts of bone marrow aspirations on 6 individuals, + exposed and 2 unexposed, are listed in Appendix 18. The differential couna showed that in 3 of 4 exposed persona there was an alteration in the mycloid-ervthroid ratio manifested by an increased number of red cell precur- sors. In addition to hyperplasia, abnormalities of chromatin material with double nucici and increased numbers of mitotic figures were seen in the normoblastic series (Figures 50 and 51). One of the exposed (No. 63) and one of the unexposed (No. 948) showed increased iymphocytosis of 33% and 27% respectively. This was reflected in the peripheral blood counts in which the vocal number of leukocytes was normal but the lymphocytes were increased to 51% and 56%. Thesignificance of this finding remains obscure, but repeat bone mar- cases during the 1965 survey. Red Cell Mees and Plaeme Volume Studies During the 1961 and 1962 surveys blood volume studies were performed on a group of Marshallese subjects and on a small number of Caucasians who had been living on the siands for one year or longer. Sodium chromate labeled with Cr*' was used to tag the erythrocytes. With body weight as a criterion, it appeared that [5 of 23 subjecu, both Marshallese and Caucauan, showed a significant reduction in red cell mass and/or plasma volume. In order to establish the relationship of blood volume to lean body masa tritiated water was administered orally to cach of 21 Marshallese subjects during the 1963 survey. In addition, determinations were made of red ceil mas and blood volume by using Cr*'-labeled sodium chromate. Table 20 Total Blood and Red Cell Volume Data (WT. = gros weaght; TBW= total body water; FAT = fat as < grom weight; LBM = lean body mam: RON :red cell volume; BV = blood volume) Subyect No. WT lke TBW. | TBW.’. FAT.“% LBM. ke RCV, | BY. | RCV/LBM, mi/kg BV/LBM, ml/kg al 34.54 48,1 63.8 44 52.1. 1.402 3.260 26.9 62.6 Ry 4h bb 25.0 5.5.0 26.4 ‘1 0.849 2.558 74.9 a2 Hib Jyh. $b $305 b).7 f44 48.3 1.428 3.320 4.6 68.7 HB bh yt U7 O22 1.6 37.1 2.108 4.053 469 710 HH bb.dt big 47.0 M7 43.6 Lid 3.196 26.4 733 875 tl. ih 45.2 94 Jo 39.1 1670 3.651 28.3 61.4 581 hi 6b $2.8 avi 46 7 1.996 4.247 44.7 95.0 HBL WF $9.9 718 0.3 54.6 yagi 3.426 20.7 62.7 4u35 bl 81 41.0 65.3 9.3 56.| 1.760 $.825 ‘$14 68.2 B45 34 90 10 213 2B.5 40.0 1070 2.488 26.38 62.2 Hh bits bb 90.4 0.0 4.5 1.091 3.0931 24.5 68.1 aH vere) my 70.5 9 1. 0.927 +905 41 623 ay +h 0 2h J 35.7 22.6 15.8 1.274 2.963 $5.6 82.8 4a 40.00 22U 34.1 249 3O.t 0.886 2.731 44 774 the 47 72 eit 47.1 4b 7.8 BAO 7150 22.8 56 9 454 nd) OO 42.2 92.8 6.7 HO 1 1Gl 2.877 26.2 63 4 rd) B.b5 248 b5.1 14 49 re | 2.150 228 oJ.4 1007 Tl So 41. 3.9 21.0 5.4 | 620 4.1535 287 747 1044 4181 26.4 b2.J 14.3 $6.2 | .066 2.664 2494 74.5 1504 bb. 43.3 4.0 11.2 59.3 1.343 3.240 3h 64.8 63.18 39.8 619 14.0 4 1.310 2.675 24.1 49.2 1.303 5.102 28.3 68.2 AY Av ACV il . Av TBW (1 = 0.059; 33.5 Ay BV it) Av TBW (1) =0.082 PRIVACY ACT MATERIAL REMOVED