PRIVACY ACT MATERIAL REMOVED
39
row examinations will be carried out in both these
Sene Merrow Examinations
The differential counts of bone marrow aspirations on 6 individuals, + exposed and 2 unexposed,
are listed in Appendix 18. The differential couna
showed that in 3 of 4 exposed persona there was an
alteration in the mycloid-ervthroid ratio manifested by an increased number of red cell precur-
sors. In addition to hyperplasia, abnormalities of
chromatin material with double nucici and increased numbers of mitotic figures were seen in
the normoblastic series (Figures 50 and 51). One
of the exposed (No. 63) and one of the unexposed
(No. 948) showed increased iymphocytosis of 33%
and 27% respectively. This was reflected in the
peripheral blood counts in which the vocal number
of leukocytes was normal but the lymphocytes
were increased to 51% and 56%. Thesignificance of
this finding remains obscure, but repeat bone mar-
cases during the 1965 survey.
Red Cell Mees and Plaeme Volume Studies
During the 1961 and 1962 surveys blood volume
studies were performed on a group of Marshallese
subjects and on a small number of Caucasians
who had been living on the siands for one year or
longer. Sodium chromate labeled with Cr*' was
used to tag the erythrocytes. With body weight as
a criterion, it appeared that [5 of 23 subjecu, both
Marshallese and Caucauan, showed a significant
reduction in red cell mass and/or plasma volume.
In order to establish the relationship of blood
volume to lean body masa tritiated water was
administered orally to cach of 21 Marshallese
subjects during the 1963 survey. In addition, determinations were made of red ceil mas and blood
volume by using Cr*'-labeled sodium chromate.
Table 20
Total Blood and Red Cell Volume Data
(WT. = gros weaght; TBW= total body water; FAT = fat as < grom weight;
LBM = lean body mam: RON :red cell volume; BV = blood volume)
Subyect
No.
WT lke
TBW. |
TBW.’.
FAT.“%
LBM. ke
RCV, |
BY. |
RCV/LBM,
mi/kg
BV/LBM,
ml/kg
al
34.54
48,1
63.8
44
52.1.
1.402
3.260
26.9
62.6
Ry
4h bb
25.0
5.5.0
26.4
‘1
0.849
2.558
74.9
a2
Hib
Jyh. $b
$305
b).7
f44
48.3
1.428
3.320
4.6
68.7
HB
bh yt
U7
O22
1.6
37.1
2.108
4.053
469
710
HH
bb.dt
big
47.0
M7
43.6
Lid
3.196
26.4
733
875
tl. ih
45.2
94
Jo
39.1
1670
3.651
28.3
61.4
581
hi 6b
$2.8
avi
46
7
1.996
4.247
44.7
95.0
HBL
WF
$9.9
718
0.3
54.6
yagi
3.426
20.7
62.7
4u35
bl 81
41.0
65.3
9.3
56.|
1.760
$.825
‘$14
68.2
B45
34 90
10
213
2B.5
40.0
1070
2.488
26.38
62.2
Hh
bits
bb
90.4
0.0
4.5
1.091
3.0931
24.5
68.1
aH
vere)
my
70.5
9
1.
0.927
+905
41
623
ay
+h 0
2h J
35.7
22.6
15.8
1.274
2.963
$5.6
82.8
4a
40.00
22U
34.1
249
3O.t
0.886
2.731
44
774
the
47 72
eit
47.1
4b
7.8
BAO
7150
22.8
56 9
454
nd) OO
42.2
92.8
6.7
HO
1 1Gl
2.877
26.2
63 4
rd)
B.b5
248
b5.1
14
49
re |
2.150
228
oJ.4
1007
Tl So
41.
3.9
21.0
5.4
| 620
4.1535
287
747
1044
4181
26.4
b2.J
14.3
$6.2
| .066
2.664
2494
74.5
1504
bb.
43.3
4.0
11.2
59.3
1.343
3.240
3h
64.8
63.18
39.8
619
14.0
4
1.310
2.675
24.1
49.2
1.303
5.102
28.3
68.2
AY
Av ACV il
.
Av TBW (1 = 0.059;
33.5
Ay BV it)
Av TBW (1) =0.082
PRIVACY ACT MATERIAL REMOVED