METAEOLISM CF ICDINE 131 Richard J. winzler, Ph.D. Associate Professor of Biochenistry School of Vedicine University of Southern Celifornia Dr. “ingzler, Associate Professor of Biochemistry at USC, will discuss recent work on the iodine metabolism and the thyroid glund using radioactive iodine, The name of the course is "Applicetion of iiuclear Fhysics" to tne bicchemist end medical sciences at the University of Celifcrnia. He will discuss notable advances recent years, using this radicactive isotore which pus in the knowledge of thyroid physiclogy and icdine metabolism which have been made in is produced et tne Atomic Energy Commission Lakeratery at Oak fidge, Tennessee ive icdine hus been found te concorityate very vaonidly in the urvebe of stall ar "tracer™ s-curta of rudicsetive ioijine sen resdily by used as a pres yek Ty Ns mat ¥ ~ syoyk -* i am ne ype i-k yoarthyroid pebicnts mey then -te given larger vherapertic amounts of rsdicactive lodine, the destructive rudietion then scleetively cestreying the Overactive thyrcid tissues in which it eceunulates. Aadicesctive tojine is elso wideiry used by eyperinentiiists to study fundismestel probicme in bislory and med the Jestitution and metabolism of lodine in the animal tedy. Dr. insler wili discuss his own work in collaboration with Dr, Paul Starr ane its relation to the work of other researchers. He has been especially interested in meking crgenic compounds containing radjczctive iodine and is using these compounds nthe study ef their fate in the aninal bo v, His studics hzve also been concerned with the influence of physiological state span the accumulctions of radioactive iodine in the thyroid glani end its incorporation into the tnyroid hormone, hte