a wt

Experimental data reported ty Boche* are surmarized below.
Ho. of

Days

20

Doss per

20

10

. Lose per

Tay (r)
&

Week (r)

60

:

durvival

Sime (Wxs)

. 2h

36

Fotal Dose

r

U4,0

83

2923

Unfortunately normal survival times were not given 20r were the ages of te

anirals, ( de 9s)
3
Y 8

se*

“
u®

Pleir** hes taxe: tie two points from boche's data, inserted tiese into
his (Blair's) equation relating reparable avd irreparable dasage. Te ratio

of insta-tansous dose to 1S day dose is 350/150 or 0.82, and for k mo ‘ths dose

aout 525/350 or 0.67.

Blair suzzests t.at "The points are toa few to determine t.6 constants

)

(of tie equation) wit

4

range,"

any accuracy but should at least Le in toe proper —

However, t:e eonstants of his aqustion ave ciecked well wit: more

exterisive data o.oi.er anicals,

‘ia equations idicate t:at tie rate of

recovery of repara le injury, is fastest

{cs the types of mrmrel sy nied)

1) the motse, aout one-islf as fast

ia te ret and aout one-sevecth asfast in tre guia pig aud dog, iut as

Blair poi. ted out thr reaction eo? t e dog is more representative of t-e larjer,
longer-lived anirels,

2irpc-20)

0: servations on Fopulations of Aniazls exyosed to C ronte Koentren

T:rsdiatio i.

2ROR-207.

Frdistions,
ae

of"

35

POC,

F.0D.

1947.

Unclassified,

A Form dation. of the Injery, Life S:an, Tose Felatisus For I-nizinr
Ji Acrlications to t.e Guinea si, 4:, @idio*,

T7520 UR RELA ae

erect.
ey
west

-lair,.

.f

ee

Select target paragraph3