‘ that in 1959 the mean erythrocyte levels were slightly lower in the exposed people. These blood elements in the Ailingnae group also showed someslight depression below the unexposed levels but not quite so marked as seen in the Rongelap exposed group. A general anemic tendencywas noted in the Marshallese, both exposed and unexposed. —n—. yo x— Price-Jones curves, on the average, showeda slight microcyvtic tendency. Serum zron levels were gen- erally normal. The fact that someof the blood ele- ments in the exposed group have not yet returned ee to the levels in the unexposed groupraises the possibility that a residual radiation effect on the bone marrow persists, but other, not immediatelyapparent, factors may be involved. 1 Reticulocyte counts have been about the same er a in the exposed and unexposed people. Bone marrow examinations on a numberofexposed individuals at 6 months and 3 years post exposure showed no abnormalities or deficiencies of cellular elements. Clinical examinations revealed no disease processes or symptoms which could be attributed to eee — —_— radiation effects, aside from skin lesions, loss of hair, and early symptoms. No specific therapy was given. Epidemics of chicken pox and measles oc- curred. The diseases encountered were no more severe or frequent in the irradiated group than in the unexposed group, even during the period of greatest depression of peripheral blood elements. At 3 years post exposure the immuneresponse to primaryand secondary tetanus antitoxin was tested and found notto besignificantly different in the exposed comparedto the unexposed popu- aan: ee lations. eS Four persons in the exposed population died of disease: {1} a 46-year-old man with a hypertensive heart disease which had been presentat the time of exposure, who died 2 years after the accident; CagERE em — * — (2) a 78-year-old man who died, 3 years after exposure, of coronary heart disease complicating diabetes; (3) a 36-year-old man whodied of acute varicella, 4 years after exposure, who hadreceived only 69 r, having been on Ailingnaeat the time of the fallout; and (4) a 60-year-old woman whodied of a cancer of the ovary at 5 years after exposure. There was no apparent relationship between any of these deaths and radiation exposure. Four deaths have occurred in the comparison popula- tion. The four deaths that have occurred in the exposed people since exposure represent a mortality Woy rate of 8.1 per 1000 population, compared with 8.3 for the comparison population and 6.8 for the Marshall Islands as a whole. Certain findings were possibly related to the radiation exposure, such as loss in weightof several pounds in most of the people during the first several months after exposure and suggestive evidence ofslight lag in growth and developmentof the children based on studies of height, weight, and bone development (but inconclusive pending verification of more exact ages of some of the children). In connection with growth and development studves, a project on the verification of accuracy of ages of the children has not been completed and, therefore, the suggestive evidence previously presented of possible lag in statural growth in the exposed children must await confirmation. It was noted, however, that in the 6-year chronological age group, three boys and onegirlout offive boys and twogirls in the exposed group exhibited significantly retarded skeletal maturation as judged by x-ray examination. The birth dates of these children seemed to befairly well established. It was difficult to evaluate the effects on fertility. However, a review of the birth rate of the exposed group overthe past 6 years seemsto indicate no noticeable effect of their exposure onfertility. The 24 births represent a rate of 48 per 1000 population, compared with 37.3 for the Marshal! Islands (1957). The 20 births over a 3-year period for the comparison population represent a rate of 62 per 1000 population. A somewhatgreater incidence of miscarriages and stillbirths has been noted in the ex- posed women, but becauseof the paucity ofvital statistics in the Marshallese and the small number of people involved, the data are not readily amenable to statistical analysis. A cardiovascular survey of the adults (1959) showed no outstanding differences between the exposed and unexposed groups. The people appearedto have less hypertension on the whole than is noted in people in the continental United States. An arthritis survey (1959) showed no great differences between the exposed and the unexposed people, and about the sameincidenceasis seen in American populations. Ophthalmological surveys showed no remarkable differences between the exposed and unexposed groups except possibly a slightly greater number of cases of pterygii, pingueculae, and cornealscars SS nn ee ne ae ge ee pee we