- 2e teal examinations showed both the exposed and unexposed people to be generally in a state of good health. No conditions were seen that could be directly related to radiation effects. ‘The incidence of various minor disorders in both adults and children was about the same in the exposed and unexposed groups. In connection with growth and development studies in the six-year chronological age group, three boys and one girl out of five boys and two girls in the exposed group exhibited significantly retarded skeletal maturation as judged by x-ray examination, but the over-all group sizes are too small to warrant interpretation. A. cardiovascular survey of the adults showed no outstanding differences between the exposed and unexposed groups. An arthritis survey showed no real differences between the exposed and the unexposed people; the incidence is about the same as that seen in American populations. An opthalmological survey demonstrated no differences between the exposed and unexposed groups except possibly a slightly greater incidence of corneal hypertrophy and scars in the exposed group. A dental survey showed no significant differences in either caries rate or incidence of peridontal disease between exposed and unexposed groups. Radiation exposure appears not to have affected dentition in the exposed children. The late effects of radiation are difficult to assess as they are those associated with normal ageing (skin looseness, elasticity, and senile changes; greying of the hair and balding; loss of accomodation, reduced visual acuity, and arcus senilis; reduced hearing; cardiovascular ehanges including blood pressure and degrees of peripheral and retinal arteriosclerosis; retrogression of neuromuscular function and hand strength were measured or estimated on a 0 to 4 + scale). Comparison of these measurements in exposed and unexposed individuals of the same age groups revealed no clear differences. Qne case of cancer developed in the exposed group five years after exposure, but this is too soon, it is believed, to be related to radiation exposure. Leukemia surveys including physical findings, studies of white cell counts and types, alkaline phosphatase staining, and basophil counts showed no evidence of leukemia or leukemic tendency. DOE ARCHIVES Genetic effects have not been specifically studied because of the small mmber of people involved. However, no apparent radiation-induced genetic changes have been detected on routine physical examination in the first-generation children of exposed parents.