99-21-1994 12:15
516262531]
ste
and vomiting on the day of exposure.
BNL-MED. DEPT.
P.010
In this group there is no furthér svidence
of effects of the exposure except the hematologic (blood) changes tha} can be de-
tected by serial studies of the blood with particular reference to lybphocytes
and platelets.
The lymphocytes reach low levels early, within 48 houfs, and may
stow little evidence of recovery for many montha after exposure.
may show some depression during the second and third week.
variation ig encountered.
The
However,
‘The late fall in the granulecytes, during
7th week, may occur and should be watched for,
granulocytes
Fonsiderable
fthe 6th or
Platelet counts reac] lowest levels
on approximately the 30th day at the time when maximum bleeding vas dbserved in
Japanese who were exnosed at Hiroshima ard Nagasaki.
This time trend in the plate
let count amd the development of hemorrhage is in merked contrast tofthat seen in
laboratory animals where platelets reach their lowest levels betveen[the 10th ani
15tn days ard henerrhage oceurs siortly thereafter.
in this group inidviduals vith neutrophil counts below 1000 per cubie mm.
nay be complcte by asymptomatic.
L,kewise, patients with platelet cbunts of 75,000
per cubic mm. or less may show no external signs of bleeding.
It 4s well known that all defenses against infection are lowerai, even by sublethal doses of radiation, and thus, patients with severe hematolo
depression
should be kept umler close observation and administered appropriate [therapy as indicated,
There is reasonably good animal experimentation to indicafe that sublethally
exposed colonies of animals are more susceptible to endemic and epidemic infection.
The numbers of individuals in greup 3 (Survival probable) willfbe greater than
in group 2 (Survival Possible) and the munber in group 2 will be mpbater than in
group 1 (Survival improbable).
Group 1 casualties will be helplessly injured.
Group 2 casualties will be able to help in their own care to a limifed extent.
Group 3 casualties will be useful and a moderate anount of work wilf
not be harmful.
No therapy other than observation is needed for thie group.
The rest of my comments will be focused on the fallout accidert
that occurred