e + aae eee . . “ COLOR PLATES Plates 3.22 and 3.23 show lesions at 53 days post-exposure. Plate 3.22 (X100, H@E) (Case #75) Loose lamination of stratum corneum with outward papil- Pilate 4.28 (X400, H&E) (Case #75) Same as 3.22. Occasional perinuclear cytoplasmic halos lary projections and resultant ‘‘rugese’’ uppearance. Stratum granulosum of good width. Basal and malpighiain fayers distinct with pigment present. Slight edema of corlum with mild telangiectasis and slight increase in perivascular lymphocytes and pericytes. Small, atrophic hair follhhele adjacent to seb:uccous gland-— in mid pars reticularis. momid stratum granulosum. Loosely laminated stratum corneum. Pigment laden chromatoPlate 3.24 shows lesions (second biopsy) at 46 days post-exposure. Plate 3.24 (X100, H&E) (Cuse #39) Narrow rugose emdermis with papillary extensions down- ward ofstratum maiphigii, Latter are heavily laden with melanotic pigment. Slight tulangicctasis of pirs papillaris and pars reticularis of dermis, Occrgional pigment laden chromalLophores in superficial dermis. ware mee phores in superficial cortum along with occaslonul lymphocytes and mononuclear phapocytes. te ee ee eT ow ery rem seteroo ee —* ~ os “es - *« > 8 es + or rs ene @ of © 2 aan . * ore a . . . = . ener e ee 8 ¢ + ere ef 8 & @ oe 8e . . . eae . ee e >» © 66s os 6 e a@ 8 @ © «@ eo © ste » * @ oo «¢« » + e #064 O88 es @ * a o * o8 “ee” PE pe Te 60