Strontium—90: decades. Some of these were young women who painted the small numerals on luminous dials, and tipped the brushes between their lips for the fine work. Some were suffering from rheumatism or other diseases, and were given radium as a therapy by some sincere physicians and by more quacks, in the 1920s before the grave danger was recognized. In all of these groups, there have been seen malignancies of bone and of blood—evident consequences of the radium irritation. Whatis striking is that the incidence of these conditions, rare in the total population, was large enough in the small numberof radium-poisoned patients to be recognized without chance of error. There is a good chance of developing a bone tumor, or leukemia, if you fix in the bones a mere speck of radium; less than one microgram, an amount 1/30,000,000 of an ounce, weighing less than the dot over an inked i. It seems very probable that, if there is a safe threshold at all here, it is below a tenth of a microgram, an amount which is a few hundred or a thousand times greater than that found in the normal skeleton. The present ICRP recommendations allow a tenth of a microgram of the stuff for workers in radiation industries, and such an allowance does not preclude the possibility of undetected subclinical changes. If we recall that there may be no threshold for somatic effects, but a straight-line relationship, and that individual responses are variable, it is reasonable to include at least a factor of 10 for safety in setting the “permissible” internal bone burden for the population at large. The UN places the normal average radium dose to the bone at a value of about 3 rads over 70 years. Somewherein the range from ten to a hundred times the background value the “permissible” valuelies. Nowthere enters a new factor: the element strontium. f \HE element strontium is relatively uncommon; its most common use is for the rich red of its flame in fireworks and flares. Like radium, it also resem- bles calcium and it also becomes stored in bone. The normal skeleton of man has about two pounds of calcium, and with it from soil and rock there has always been deposited about a tenth of a teaspoonful of strontium. Normal (pre-atomic-bomb age) strontium presents no hazard, so far as anyone knows; it is not radioactive. But every explosion of a nuclear bomb spreads into the high air with its fireball a new radioactive isotope of strontium, strontium-90. It comes from fission, and the old-style fission bomb and the new-style fission-fusion- fission bomb both contribute strontium-90. (The yet undeveloped “clean” bomb will contribute proportionately less as it makes less use of fission energy; no one has yet discovered how to eliminate the stuff entirely.) So far some 200 pounds of strontium-90 have been garried aloft by the churning hot gases of the mushroom explosions. It has spread worldwide. It falls out of the upper atmosphere, in a manner not yet fully understood. It comes down slowly with rain and snow, on river and reservoir, plant leaf, and soil, Some of it is taken up chemically through the roots of plants to become part of grass or seed, and eventually part of the glass of milk or the rice in the bowl. In the U.S., about 80 per cent of the minute quantity which enters our bodies comes to us in our milk. In Japan more than two-thirds comes from rice. Un- polished or whole-wheat, unfiltered rain water, and similar items of diet, such as vegetables, may also contribute a significant amount of strontium-90. If there never are any AVERAGE STRONTIUM-90 IN BONES Units more explosions, the fallout from tests already made will reach a maximum about 1970, rising to two and a half or Children, three times its present value, and then will decline slowly for a generation or two. IN SSCHENCE”: 127, 269. 1988 There is not much of it. The load of strontium-90 in 0.2 5 0.1] 0 Adults : memes 1954-55 1955-56 1956-57 Notable amounts of strontium are absorbed only by growing bones. Averages above were calculated on the basis of data compiled from four U.S. cities 106 MARCH 1959 $ your front yard is likely to be about one-tenth of a microgram. It is spread down into the topsoil by rain and plant growth and hoe and worm; how much is taken up by plants depends on a wide variety of conditions—upon the depths of their roots, the chemistry of the soil, the distri- bution of rainfall, and so forth. But it is out there, and it enters the food chain and, from there, the bone. Amongall the scores of constituents of fallout, strontium90 is especially hazardous because it is released in con- siderable quantity (it forms a few per cent of all radioactive products of fission), it seeks the bone, and it stays there a long time. Some of the other radioactive products decay so quickly that they cannot pass through the long chain of events to reach the target; some which have a long life do not accumulate in the body; but strontium-90 lasts on the average about 40 years and it accumulates in bones. What wili strontium-90 do in bone? Both general theory and direct animal experiments (with rather heavy

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