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for maa, qunea poz, am mouse, respectively tHeterence ate On this usis, Cue arse fo nan

was estiremed by tainey eae sixth of ihe mouse dose vaices 26s Cow hall of the guines pig dose
values. Tke results cf Urede calculations fer the individecl ergte Gases for the early period
(0 to 53 bacrs) and the significant long-term period(3 to 7 days) art presented in Totes 3.
and RIS. Esticizted doses for man derived from the guinea pig and mouse Asta are i cieze
agreement. This can Ge taken a8 Supporting evidence for the tacvury that ihe inhaled walame of
alr per minute pet gram cf iissue 7s an lmporicat determina of the interns! conawiration ja
the animals stedled, The differences that do exist beteecs Cases tc sia, culeslaier: from the
mouse and guinea pig data, may have heen de in part to the varying seus of seli-ticking by

these animls (although the skins of these aniouls were 24 ieeludéd ii nad of the wsieulations,
they were found té be Lishly comaminated with radioactivity}.

.

.

3.33 Assessment ef the toter Kazard te San. Whole Body Dase versus Dose
to fudieidual Orean,
Radiation symirome ond re latite dose are based on consideration
of the whole au.fral. Thea, 50 r to the whole animal ivats le a transwert reduction in white > -

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vilood celis. Tie esfects of 50 r toa piven orpan carat be described in terms of shite biood

cell level. Similarly, ach descriptions as “geuerahzed walaise, erythenia and vomiting” loa”
other whole-body doses would be meaningless when applied to iadwideal erpans such as the
bone marrow, Gi tract, =nd thyrnid. Thux, in considering the efiects of zn early cose (whether
it ke exteraal or intersal) thet would lead to an immediate bictegical effect discernittie 24 redhation symirome, the ceee to the whote indy is more meaniagh..
:
Bowever,-a: expected, the data imhecates thet tie radialsitrity i9 crecentrated ia certaia.
.
Orgaaed thal some cf Uese urgais are coasideratty Taare radissersilive thar ctiecs. Thos,
the uae of the dese ta thy thote body (otal rihiertifeity dviced
od Dy the whe’ + Rely wsactel te
Denoeieee
Geterna ne the eater radittion’ symireme would ignore tke [seu that certain hs
ae
Organs, Le., critic8 copmon, are avsorbirg a greater Purl 4! tle absorbed coorey.
Ths problem caa ie vesolyed by re ating ike Goce abrerbed by the eriiless oygos as if it
were 222 dase to the whole bady, iv. a dese of 50 + to the siehitca then wetukl be cau Wered
asadéose cl 50 r to the strote hocy. in this way, th: hazard sould be everestimaicd, allowing
as: ieiy factor to Ge insetporaied into the ealeuisied ralecs.
‘
isternal Dose to- Nan, Calculated ca the Basis o
: f Critheas Organs.
:
: Prior to lay consigeraiica of ile internal case, it should be noted thei adaqucie shiriging eal *
be necessacy to reece te external gamma dotes, which ramre from 2,153 to 51 r fer Wahoo
and 329 to 72 ¢ for Usnbret', before tigress externalor imercal Gollyexposures woud be
Meniting factors in operational coriitions. However, it is with this icgress radivactivity, which
*, €an irradiate personsel from the outsideor, when absorbed iio the body, ‘tradicte on interrad
emitich, that the present study is concérned.
The rerults of the conversion of animal dose to dose to:inam, are given in Tattes 3.23 ond
3.25. Several doses on the director platform exceeded 25 to £0 rads, the dase level that would
result in fi: .t Signs of hematolog.c changes. The highest value, 177 rads, would oot result iz

any deaths, but 2generaiiaed malaise, changes in Lioed picture, and vomiting coald result,

However, these internal doses wero not a result 01 ingress radioactivity but were duc to local
fallout ard probahiy water of the buse surge.

3.4

CORRELATION OF AIR SAMPLE axD ANIMAL DATA

:

:

The data ottained was inadequate to-provice any trav correjatiun between air samnie and
animal data. The only evidence that such 2 correlation mictt be possible is presenied in Talte

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9.26.

Early wiwle-inety internal doses hive approximaiciy the same relation to sath other as

do the adjacent air sample activities for the various test comnartwents.

Direclor plaerm

data dus neg follow thisgeneral trend, indicating a severe bias between animal and air sam-

Plausg.

sinimals and air samples were located on apposite Sucks of the platforra ant ray hare

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