66 of greatest radio element deposition. In fact, we could make very real correlation between radio element deposition and histopathological. A few patients that we were able to do extensive pathological studies on, we could find that there are many areas -- not many, but in some areas -- in which the transition from this formation from atypicalosseous. tissue and the fiber sarcomas was awfully hard to differentiate. Alderson Reporting Company Washington, D. C Dr. Lipscott at Chicago has reviewed this and some of his 10 work with plutonium in rats. 11 likely place for the formation of these tumors around these 12 areas of atypicalosseous formation, most of the tumors. have 13 developed, on the ends of the long bones in thecancerous 14 bones. 15 conclusions are probably correct. 17 cancer. 18 small areas in whih you have the proliferation of this 19 tiesue become malignant? 20 years, and then suddenly there is a turnover, and then it 21 seems to spread throughout the skeleton or even multiple 22 23 ARC 24 25 e r. Cneray‘ High? oan supportive evidence that these I think this ultimately gets down to what causes 16 pepartment ae All of this is The feeling is that the most Is it one cell from the irradiation in these There is a smoldering of this for tumor formation throughout the skeleton. As far as permissible levels areconcerned, we have to interpret that in terms of this pathological finding in these people. It is to set a level with this marked ,