oe C Getotien predace dimage umexecced Lem laborctcry inform.tion. It should be heve peinted out thet many cf the biclogical effects regerted or observed upon orgenisms ot Hiroshima, Magcsakd, end Bikini for exceeded these which would bs expected on the besis of data availeble from instrumentation at rinity ord Bikini, es extrapolated and interpreted to arees in the actual bombed cities. Whether this re_rzsents a decreased instrument sensitivity or response due to icn saturction sonditicns, merkedly incrcesed biclogical response to the seme shsnomenon, other operative mechanisms, or a esbinction of any or 211 of the above res‘ons2s i3 rt sresent en wnansvercd qvostion. There is considerable nesd for further laborrtory work on fest exposures. Data from more closely controlled ololocical and physiccl tests apeer imperative to answer this problem. Fro,er cerrelation and comrerigzon of these tecting methods might give mutually sudporting date. Vell Teelibrated" tost orgonisms at present 2, e-r to be mice, corn, If a second memmalion s_eciss 1p esral Dresopnila, and Tredescantia. mercctory sonsiderable "eallbrotion" work would heve to be dene veguralec of ths choice of msemel to be used. rats, hemsters, or gvinsa pigs. Tre choice would probdzbly ve Yetcrem It is not believed th: t oufficient deta exiats upon the response to radinticn to consider other orgenisms "calibrated." wel Acceptense of this view rules out dogs, cats, geats, shscn, end swine as test orgarisms. Due to the confusion concerning secific tissue or organ systcm quantitetive res.onse in mewmils, the best criterla for observetion of these mammals :culd a,;-ear to be seute leth lity, longevity es reflected in the mean life span of survivors of acute lethal effevts, and possibly genetic studies of theses survivors. vs Memmealien exveriments visuvlined tien consist of exposure of rersonably sarge but not unwielcy groups of sice fend perhars one other merrel to de 2 esiscted as above indiceted) in im:edicte proxieity to physie 1 mearuve- | DOM ARCHIVES -