that particle size greatly affected the amount of deposition
in the areolar spaces with increases of as much as 10-fold with
a reduction of mass-median diameter from 2.6 to

.45 nn.

Taplin

et al.? found that in rats lung retention of particles with a
mean size ofn~-lp was strongly dependent upon density of the
particles.

Autoradiographs of lungs of rats collected for the present
work indicate a diffuse deposition of the radioactive material
within the lungs except for the bronchii, where the activity is

more concentrated and irregular (Fig. 13).
The results found in the autoradiographs as well as the
lack of appreciable variation in samples may well be dependent
upon the factors of selection and retention of particles by

size and density, especially since the particles retained by the
lungs are of & small mean diameter and are more nearly the density of the heavier Nevada sand and BaSo, particles than the
“aye particles Taplin found to be retained to @ greater degree

in lungs of rats.
The least variability in organs and tissues of the post
shot rats was found in the liver,

the variability of kidney

and lung being slightly greater.
When the average values for each organ or tissue of the
post shot rats are compared,

muscle is the lowest and bone

the highest in activity of the samples taken.
however,

Lung tissue,

is almost as low as that of muscle tissue.

In the birds from Rigili,

Rojoa, Aaraanbiru,

7 wae

and Runit

Select target paragraph3