- 20 # . * In the context of his comment it is interesting to refer to the National Academy of Sciences, National Research Council report of 1961 on the Effects of Inhaled Radioactive Particles. [{c] The first sentence reads, "The potential hazard due to air- borne radioactive particulates is probably the least understood of the hazards associated with atomic weapons tests, production of radioelements, and the expanding use of nuclear energy for power production." A decade later that statement is still valid. Finally let me quote Drs. Sanders, Thompson, and Bair from a paper given by them last October. [d] Dr. Bair and his colleagues have done the most relevant plutonium ‘oxide inhalation experiments. "“Nonuniform irradiation of the lung from deposited radioactive particulates is clearly more carcinogenic than uniform exposure (on a total-lung dose basis), and alpha-irradiation is more “sf carcinogenic than beta-irradiation. The dceses reguired for a substantial tumor incidence, are very high, how- ever, if measured in proximity to the particle; and, again, there are no data to establish the low-incidence end of a dose-effect curve. And there is no general theory, or data on which to base a theory, which would permit extrapolation of the high incidence portion of the curve into the low incidence region." I agree and I suggest that in such a circumstance it is appropriate to view the standards with extreme caution. 31 {c} U. S. NAS-NRC Subcommittee, Effects of Inhaled Radioactive Particies. Report cf the Subcommittee on Inhalation Hazards. Committee on Pathologic Effects of Atomic Radiation. Naticnal Academy of Sciences - National Research Council, Wasnington, 848, (a] NAS-NRC/PUB-648, 1961. D. C. 1961. Publication Sanders, C.L., R.C. Thompson, and W.J. Bair, Cancer: In: Inhalation Carcinocenesis. Division, Proceedings of a Biclogy Oax Ridge National Laboratory, conference heid in Gatlinburg, Tennessee, October 8-11, 1969. Hanna, "Lung Dose Response Studies with Radionuclides." Jr., P. Nettesheim, and J.R. Gilbert, M.G. | eds., U. S. Atomic Eneray Commission Symposium Series 18, 1970. pp. 285-303. (CONF-691001). 31/ Geesaman, Donald P., “Plutonium and Public Nealth," >} Lawrence Livermore Laboratory, Calif., GT-121-705, Avril 19, 1970, reproduced in Unterarciund Uses of Nuelesr Erercv, Part 7 . . 7 ~ Vtl.s. before the Suboosstitice PALLY Ang water= PelbLocuLron or : the wee ae ee, —_ é iG ric -_ Committee on Paulie Works, _ ae U. AA S. Senate, Gist Conarese, ini fo-s> ae