Long term effects in survivors:

The life spen,

tumor incidence and catarect induction will be

stidied in surviving mice exposed both to neutrons
end

gemna

OQ

reys.

These enimels will be sent Db

air to Furth at Cesk Ridge f-r observation.
Gamma ray Survivors:

There will be about

200 enimels at 2ach of the

29 ganye ray

stations earnearsed for long term survival

Studies.

Following the shot, they will

be pooled in grouvs of four (covering a
dose range of 100 roentgens).

Not more

then 4200 animals will be returned to the
states.

They will be accompanied by controls

(? how many) which will be given equivalent
doses of 250 k.v. x-rays (for each individual
group,

not the pooled groups of four)

according to the mouse dosimetry nessure-

ments (My ovm oninion is that since noase
dosimetry is @ rather new tool for celi-

bration of radiation they should also have
control a@ninals given doses based on the
-hysical measurements of what the enimels
received.

“his would alley possible

controversy in the future as to the signif-

icence of the results.)

The difference in

life sosan, tunor incidence and caterect
development between the animals exnosed in
the field end those given ecuivalent doses
f 250 k.v. x-reys will be studied.
<

Ge

Only

200 non-irradisted controls will eclompany
the expesed animels.

The statisticians

felt that no more were necessary since the
differences

in long tern effects between

mo een

oy

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