9 it was believed possible that these lesions might not respond well to trauma, all biopsy lesions healed per primam. There was no evidence that the intense sunlight to which these people were exposed had adversely affected any of the lesions. There appeared to be no evidence of any change which would suggest malignancy. Histopathology Biopsies were taken from 15 lesions showing residual changes. stains were used on all biopsies: 1) hematoxylin and eosin; The following 2) Mallory, for connective tissue; 3) Verhoeff, for elastic tissue fibers; 4) phosphotungstic acid hematoxylin, for fibrils; 5) Mayer's mucicarmine stain, for mucin; and 6) Rinehart's acid mucopolysaccharide, for mucopolysaccharide. Comparison was made with control biopsies taken from the neck, antecubital fossa, anddorsum of the foot of nonexposed Marshallese. At the time special staining of sections from earlier biopsies were not available, However, a detailed description of comparative changes between the two-year and earlier sections will be given in a future report, The following changes were noted in the two-year postexposure sections of the biopsies: 1. No neoplastic lesions were present, 2. No epidermal cellular alterations suggestive of a precancerous condition were seen. . aw Oe. PES:POPtnaFm! 7 SENDee (ae o Figure 7. Section from lesion of back of neck, 512X. There is some loss of pigment in the basal layers of the epidermis and telangiectasis in the dermis. Figure 8, Section from ear lesion, 512X. There is a heavy deposition of collagen in the papillary and reticular layers of the dermis. Case #79 Case #39 (Table 3). {Table 3).

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