“An situations where the 24 hour iodine image differs substantially from
the technetium image.
With this technique it should be possible to evaluate the effects of
washout with small doses of intravenous perchlorate.
It may be possible
to localize areas within the gland where there may be a binding deficit and
to quantify the binding of iodine at these very early times after
administration.
CONCLUSIONS
Both technetium-99m and iodine-123 can be used to advantage in
assessing thyroid function and anatomy.
They have similar principal gamma
photons and their short physical half-lives result in low radiationdose,
thus allowing administration of large quantities of activity.
The very
early uptakes of these radionuclides by the thyroid do not bear a consistent relationship and this requires further study.
The clinical value
of iodine-123 depends on its being consistently available at a reasonable
cost.
5001361